42438-89-1

Usage

Uses

Used in Pharmaceutical Industry:
Pinostilbene is used as a pharmaceutical agent for its potential health benefits. It exhibits anti-inflammatory, antioxidant, and antiplatelet aggregation properties, making it a promising candidate for the development of drugs targeting various diseases.
Used in Cosmetic Industry:
In the cosmetic industry, Pinostilbene is used as an active ingredient for its anti-aging and skin health-promoting properties. Its antioxidant and anti-inflammatory actions contribute to maintaining skin vitality and reducing the appearance of wrinkles.
Used in Nutraceutical Industry:
Pinostilbene is also utilized in the nutraceutical industry as a dietary supplement. It is believed to have potential health benefits, such as improving cardiovascular health and supporting the immune system, due to its various bioactive properties.
Used in Research Applications:
In research settings, Pinostilbene serves as a valuable compound for studying the effects of stilbenoids on cellular processes and their potential applications in medicine and healthcare. Its unique structure and properties make it an interesting subject for scientific investigations.

Biochem/physiol Actions

Pinostilbene is a resveratrol derivative that induced apoptosis in several cancer cell lines.

InChI:InChI=1/C15H14O3/c1-18-15-9-12(8-14(17)10-15)3-2-11-4-6-13(16)7-5-11/h2-10,16-17H,1H3/b3-2+

Upstream product

• 22255-22-7 3,5,4'-trimethoxy-trans-stilbene 
• 185249-89-2 2-(3,5-dimethoxyphenyl)-1-(4'-methyoxyphenyl)ethan-1-ol 
• 537-42-8 3,5-dimethoxy-4'-hydroxy-trans-stilbene 
• 501-36-0 (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol 
• 74-88-4 methyl iodide 
• 68692-55-7 1-Benzyloxy-3-[(E)-2-(4-benzyloxy-phenyl)-vinyl]-5-methoxy-benzene 
• 50637-28-0 (3-(benzyloxy)-5-methoxyphenyl)methanol 
• 50637-26-8 methyl 3-(benzyloxy)-5-methoxybenzoate 
• 58026-13-4 1-(benzyloxy)-3-(bromomethyl)-5-methoxybenzene 

Downstream Products

• 58762-96-2 3,4'-dihydroxy-5-methoxy-trans-stilbene 4'-O-β-D-glucopyranoside 
• 67884-29-1 3,4'-dihydroxy-5-methoxybibenzyl 
• 1511857-26-3 (E)-4-(3-hydroxy-5-methoxystyryl)phenyl 2-acetoxybenzoate 
• 1235867-69-2 C₁₅H₁₄O₆S 

Relevant academic research and scientific papers

Method for synthesizing artificially all-trans-resveratrol and derivative thereof

The invention discloses a method for synthesizing artificially all-trans-resveratrol and a derivative thereof. In the method, the precursors of all-trans-resveratrol and the derivative thereof are prepared by means of constructing a conjugated fused ring, thus the all-trans-spatial structure of resveratrol and the derivative thereof is restricted completely, to prepare all-trans-resveratrol and the derivative thereof. The resulting product of the preparation method of 1,2-stilbene or the derivative thereof in the invention is of all-trans configuration, so as to meet the demand of biologically active substance chemicals. Compared to the previous processes, the method provided by the invention has the advantages of simple processes and mild conditions, thereby meeting the green chemistry concept.

Alkyl derivative manufacturing method

PROBLEM TO BE SOLVED: To provide a new method for producing an alkyl derivative of a polyphenol. SOLUTION: The method for producing an alkyl derivative of a polyphenol includes a step of reacting an acetic acid salt and an alkylating agent with the polyphenol. COPYRIGHT: (C)2013,JPOandINPIT

Antifungal activity of resveratrol derivatives against Candida Species

trans-Resveratrol (1a) is a phytoalexin produced by plants in response to infections by pathogens. Its potential activity against clinically relevant opportunistic fungal pathogens has previously been poorly investigated. Evaluated herein are the candidacidal activities of oligomers (2a, 3-5) of 1a purified from Vitis vinifera grape canes and several analogues (1b-1j) of 1a obtained through semisynthesis using methylation and acetylation. Moreover, trans-ε-viniferin (2a), a dimer of 1a, was also subjected to methylation (2b) and acetylation (2c) under nonselective conditions. Neither the natural oligomers of 1a (2a, 3-5) nor the derivatives of 2a were active against Candida albicans SC5314. However, the dimethoxy resveratrol derivatives 1d and 1e exhibited antifungal activity against C. albicans with minimum inhibitory concentration (MIC) values of 29-37 μg/mL and against 11 other Candida species. Compound 1e inhibited the yeast-to-hyphae morphogenetic transition of C. albicans at 14 μg/mL.

Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent

An emulsion cosmetic composition comprising at least one resveratrol derivative, an aqueous phase, and an oil phase having at and at least one oil phase structuring agent, and a method for preparing emulsions capable of delivering active resveratrol to the skin.

Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant

An emulsion cosmetic composition comprising at least one resveratrol derivative, an aqueous phase, and an oil phase, having at least one silicone surfactant, and a method for preparing emulsions capable of delivering active resveratrol to the skin.

Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent

An aqueous based cosmetic composition comprising at least one resveratrol derivative and a water phase containing at least one aqueous phase structuring agent; or an emulsion composition comprising at least one water phase, at least one oil phase containing at least one nonvolatile silicone, and at least one resveratrol derivative.

Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone

An emulsion cosmetic composition comprising at least one resveratrol derivative, a water phase, and an oil phase containing at least one linear or branched volatile or near volatile silicone and a method for delivering active resveratrol to the skin.

Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives

An anhydrous color cosmetic composition comprising at least one resveratrol derivative and particulates; and an anhydrous emulsion skin care composition.

PREVENTION AND TREATMENT OF COLON CANCER

Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.

Chromium arene complexes in synthesis of trans-resveratrol

Two variants of synthesis of resveratrol (3,5,4′ -trans-trihydroxystilbene) from dimethyl ether and anisaldehyde were performed using the chromium η6-benzenetricarbonyl complex. The Wittig-Horner reactions or aldol condensation in four stages followed by demethylation by EtSLi were applied.