25912-16-7

Basic information

• Product Name: m-(1-pyrrolidinyl)phenol
• Synonyms: m-(1-pyrrolidinyl)phenol;3-(1-Pyrrolidinyl)phenol;3-Pyrrolizinophenol
• CAS NO: 25912-16-7
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.21632
• EINECS: 247-338-7
• Mol File: 25912-16-7.mol
• Article Data: 27

Chemical Properties

• Melting Point: 133-134 °C
• Boiling Point: 324.7°Cat760mmHg
• Flash Point: 181°C
• Appearance: /
• Density: 1.146g/cm³
• Vapor Pressure: 0.000128mmHg at 25°C
• Refractive Index: 1.594
• PKA: 10.08±0.10(Predicted)
• CAS DataBase Reference: m-(1-pyrrolidinyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: m-(1-pyrrolidinyl)phenol(25912-16-7)
• EPA Substance Registry System: m-(1-pyrrolidinyl)phenol(25912-16-7)

Safety Data

• Hazardous Substances Data: 25912-16-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13NO/c12-10-5-3-4-9(8-10)11-6-1-2-7-11/h3-5,8,12H,1-2,6-7H2

Upstream product

• 123-75-1 pyrrolidine 
• 108-46-3 recorcinol 
• 19805-73-3 3-(pyrrolidin-1-yl)cyclohex-2-en-1-one 
• 53199-31-8 bis(tri-t-butylphosphine)palladium⁽⁰⁾ 
• 42471-59-0 1-bromo-3-(methoxymethoxy)benzene 
• 57-09-0 cetyltrimethylammonim bromide 
• 591-20-8 3-Bromophenol 
• 115833-93-7 3-pyrrolidin-1-yl-phenylamine 
• 74-96-4 ethyl bromide 
• 591-27-5 m-Hydroxyaniline 
• 110-56-5 1,4-dichlorobutane 
• 626-02-8 3-Iodophenol 
• 110-63-4 Butane-1,4-diol 
• 14318-66-2 3-methoxy-N-methylaniline 

Downstream Products

• 110475-28-0 1-(3-hydroxy-phenyl)-1-methyl-pyrrolidinium; iodide 
• 37895-34-4 4-phenyl-7-pyrrolidin-1-yl-benzo[e][1,3]oxazin-2-one 
• 37895-33-3 N-benzoyl-2-hydroxy-4-pyrrolidin-1-yl-benzamide 
• 1152500-27-0 C₁₄H₁₉NO 
• 74427-40-0 2-hydroxy-4-(pyrrolidin-1-yl)benzaldehyde 

Relevant articles and documents

OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING

This invention concerns novel oxazine-based fluorophore compounds useful in invivo nerve imaging, as well as compositions comprising them and methods for their use.

NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION

Nerve-specific fluorophore formulations for direct or systemic administration are described. The formulations can be used in fluorescence-guided surgery (FGS) to aid in nerve preservation during surgical interventions.

Inter-alkane amidogen phenolic synthetic method (by machine translation)

Inter-alkane amidogen phenolic synthetic method, its characteristic is: 1st step, between the two alkane amidogen acyl aniline and sulfuric acid aqueous solution mixing and heating to 50 - 110 °C, thermal insulation reaction of aniline [...] sulfuric acid aqueous solution; 2nd step, continue to drip the sodium nitrite aqueous solution, sodium nitrite aqueous solution for dropping temperature of - 10 - 20 °C, drop bi yu 5 - 30 °C insulation, [...] aniline obtained diazonium salt of the sulfuric acid aqueous solution; 3rd step, [...] aniline diazonium salt of the sulfuric acid aqueous solution is directly heated to 45 - 110 °C, thermal insulation, in the hydrolysis reaction of the diazonium salt, cooling after treatment, to obtain the product between two alkane amidogen phenol; three-step required by the reaction of sulfuric acid in the 1st step reaction in the finished disposable adding; a three-step reaction in a finish step by step in the pot. The method of the invention with raw materials are cheap, abundant, synthetic high security of the process, the product yield is high, the three waste less pollution and the like, has high industrial value. (by machine translation)