424839-33-8

Upstream product

• 412021-12-6 Phenyl-methanesulfonic acid (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 556-56-9 allyl iodid 
• 1939-99-7 benzenesulfonyl chloride 
• 2595-05-3 Diacetone D-glucose 
• 106-95-6 allyl bromide 

Downstream Products

• 688801-46-9 (3R,5S)-5-methyl-3-phenyl-1,2-oxathiolane 2,2-dioxide 
• 502464-39-3 (3R,5R)-5-methyl-3-phenyl-1,2-oxathiolane 2,2-dioxide 
• 756472-43-2 (R)-1-phenyl-3-butene-1-sulfonic acid 

Relevant academic research and scientific papers

Efficient asymmetric synthesis of α-alkylated benzylic methyl sulfonates

The first highly efficient auxiliary-controlled synthesis of various α-substituted sulfonic acid derivatives is described. Alkyl or aryl halides were reacted with lithiated benzylic sulfonic esters bearing 1,2:5,6-di-O-isopropylidene-α-d-allofuranose as a

Asymmetric Synthesis of α,γ-Substituted γ-Sultones via Allylation of Chiral Lithiated Sulfonates

The first auxiliary controlled asymmetric synthesis of enantiopure α,γ-substituted γ-sultones via α-allylation of lithiated sulfonates by using 1,2:5,6-di-O-isopropylidene-α -D-allofuranose as chiral auxiliary is described. The high asymmetric inductions

The first highly efficient asymmetric synthesis of α-substituted methyl sulfonates

The right choice of sugar auxiliary led to a breakthrough in the first asymmetric α-alkylations of sulfonic acid esters (see scheme). The high asymmetric inductions were reached with 1,2:5,6-di-O-isopropyliden-α-D-allofuranose as the auxiliary group, whic

A practical approach towards the asymmetric synthesis of α,γ-substituted γ-sultones

The first auxiliary controlled synthesis of enantiopure α,γ-substituted γ-sultones via α-allylated chiral sulfonates is described. The high asymmetric inductions of the α-allylations were reached with our previously described auxiliary 1,2:5,6-di-O-isopro