42520-97-8

Basic information

• Product Name: N,N-Bis(2-chloroethyl)-1-butanamine
• Synonyms: N,N-Bis(2-chloroethyl)-1-butanamine;N,N-Bis(2-chloroethyl)-N-butylamine;TL-513
• CAS NO: 42520-97-8
• Molecular Formula: C₈H₁₇Cl₂N
• Molecular Weight: 198.16
• Mol File: 42520-97-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.35°C (rough estimate)
• Flash Point: 63.9°C
• Appearance: /
• Density: 1.1707 (rough estimate)
• Vapor Pressure: 0.824mmHg at 25°C
• Refractive Index: 1.6100 (estimate)
• CAS DataBase Reference: N,N-Bis(2-chloroethyl)-1-butanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Bis(2-chloroethyl)-1-butanamine(42520-97-8)
• EPA Substance Registry System: N,N-Bis(2-chloroethyl)-1-butanamine(42520-97-8)

Safety Data

• Hazardous Substances Data: 42520-97-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H17Cl2N/c1-2-3-6-11(7-4-9)8-5-10/h2-8H2,1H3

Upstream product

• 102-79-4 n-butyldiethanolamine 
• 55112-89-5 n-butyl-bis(2-chloroethyl)amine hydrochloride 
• 109-65-9 1-bromo-butane 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 

Downstream Products

• 42520-99-0 1-butyl-4-phenyl-piperidine-4-carbonitrile 
• 1332713-62-8 butyl-N,N-bis[((2'-benzylaminoformyl)phenoxyl)ethyl]amine 
• 212770-83-7 1-butyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester 
• 98561-35-4 butyl-bis-(2-chloro-ethyl)-amine oxide 

Relevant articles and documents

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Synthesis, characterization and luminescent properties of lanthanide complexes with an unsymmetrical tripodal ligand

Solid complexes of lanthanide nitrates with an novel unsymmetrical tripodal ligand, butyl-N,N-bis[(2′-benzylaminofomyl)phenoxyl)ethyl]-amine (L) have been synthesized and characterized by elemental analysis, infrared spectra and molar conductivity measurements. At the same time, the luminescent properties of the Sm(III), Eu(III), Tb(III) and Dy(III) nitrate complexes in solid state were also investigated. Under the excitation of UV light, these complexes exhibited characteristic emission of central metal ions. Copyright

N-hydroxy-2-(Alkyl,Aryl or Heteroaryl sulfanyl, sulfinyl or sulfonyl) 3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

Matrix metalloproteinases (MMps) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenases, stromelysins and gelatinases. TNF-α converting enzyme (TACE), a pro-inflammatory cytokine, catalyzes the formation of TNF-α from membrane bound TNF-α precursor protein. It is expected that small molecule inhibitors of MMPs and TACE therefore have the potential for treating a variety of disease states. The present invention provides low molecular weight, non-peptide inhibitors of matrix metalloproteinases (MMPs) and TNF-α converting enzyme (TACE) for the treatment of arthritis, tumor metastasis, tissue ulceration, abnormal wound healing, periodontal disease, bone disease, diabetes (insulin resistance) and HIV infection. The compounds of this invention are represented by the formula where R1, R2, R3and R4are described herein.