425394-08-7

Upstream product

• 51173-57-0 2,6-diaminopurine-N²,N⁶-dibenzoate 
• 425394-07-6 N²,N⁶-dibenzoyl-9-(2',3'-di-O-benzoyl-α-L-threofuranosyl)-2,6-diaminopurine 

Downstream Products

• 425394-11-2 N²,N⁶-dibenzoyl-9-{2'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}-2,6-diaminopurine 
• 425394-09-8 N²,N⁶-dibenzoyl-9-{3'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}-2,6-diaminopurine 

Relevant academic research and scientific papers

2,6-Diaminopurine in TNA: Effect on Duplex Stabilities and on the Efficiency of Template-Controlled Ligations

(Matrix Presented) Replacement of adenine by 2,6-diaminopurine - two nucleobases to be considered equivalent from an etiological point of view - strongly enhances the stability of TNA/TNA, TNA/RNA, or TNA/DNA duplexes and efficiently accelerates template-

The α-L-Threofuranosyl-(3′ → 2′)-oligonucleotide system ('TNA'): Synthesis and pairing properties

Our studies of α-L-Threofuranosyl-(3′ → 2′)-oligonucleotides ('TNA') are part of a systematic experimental inquiry into the base-pairing properties of potentially natural nucleic acid alternatives taken from RNA's close structural neighborhood. TNA is an efficient Watson-Crick base-pairing system and has the capability of informational cross-pairing with both RNA and DNA. This property, together with the system's constitutional and (presumed) generational simplicity, warrants special scrutiny of TNA in the context of the search for chemical clues to RNA's origin.