42566-83-6Relevant academic research and scientific papers
Photorearrangement of N-alkanoyl β-enaminones. Application to the synthesis of α-amino-β,γ-unsaturated acid derivatives
Amougay,Letsch,Pete,Piva
, p. 2405 - 2420 (2007/10/03)
The irradiation of N-alkanoyll-β-enaminones lead to the formation of spiranic β-lactams which undergo C-N bond cleavage during chromatography on alumina giving cycloalkenones functionalized at position 3. This new rearrangement has been applied to the synthesis of α-amino-β,γ-unsaturated amides in one step and gives convenient yields.
