425702-18-7 Usage
Uses
Used in Pharmaceutical Industry:
4,5-Difluoro-2-methoxybenzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its role in inhibiting 5-lipoxygenase, an enzyme associated with inflammation. This makes it a valuable component in the development of drugs targeting inflammatory conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4,5-Difluoro-2-methoxybenzoic acid is utilized as an intermediate in the production of agrochemicals, potentially contributing to the development of new pesticides or other agricultural products that can enhance crop protection and yield.
Used in Anti-inflammatory Applications:
4,5-Difluoro-2-methoxybenzoic acid is employed as an anti-inflammatory agent due to its inhibitory effect on the 5-lipoxygenase enzyme, which is instrumental in the inflammatory process. This application is particularly relevant for conditions where reducing inflammation is beneficial.
Used in Asthma Treatment:
4,5-DIFLUORO-2-METHOXYBENZOIC ACID is studied for its potential use in treating asthma, a respiratory condition characterized by inflammation and constriction of the airways. By inhibiting 5-lipoxygenase, it may help alleviate symptoms associated with asthma.
Used in Cancer Treatment Research:
4,5-Difluoro-2-methoxybenzoic acid is also being investigated for its potential role in cancer treatment, given its biological activities and the possibility of targeting specific pathways involved in cancer progression. This research avenue could lead to new therapeutic approaches for various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 425702-18-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,5,7,0 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 425702-18:
(8*4)+(7*2)+(6*5)+(5*7)+(4*0)+(3*2)+(2*1)+(1*8)=127
127 % 10 = 7
So 425702-18-7 is a valid CAS Registry Number.
425702-18-7Relevant academic research and scientific papers
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation
Shchegol'kov,Trefilova,Borisevich,Shchur,Ljushina,Khursan,Burgart, Ya.V.,Solodnikov, S.Yu.,Saloutin,Markova,Maslova,Krasnykh
, p. 91 - 99 (2016/12/22)
We have developed the convenient methods for synthesis of polyfluorosalicylic acids and their derivatives. For the first time the biological properties of polyfluorosalicylates were investigated in vitro (permeability through the biological membranes, COX-1 inhibitory action) and in vivo (anti-inflammatory, analgesic activities, acute toxicity). Molecular docking of polyfluorinated salicylates confirmed in vitro and in vivo experiments.
A convenient and efficient approach to polyfluorosalicylic acids and their tuberculostatic activity
Shchegol'Kov, Evgeny V.,Shchur, Irina V.,Burgart, Yanina V.,Saloutin, Victor I.,Solodnikov, Sergey Yu.,Krasnykh, Olga P.,Kravchenko, Marionella A.
supporting information, p. 2455 - 2458 (2016/07/07)
We have developed the practical method for polyfluorosalicylic acids synthesis via nucleophilic ortho-mono-substitution of fluorine atom with magnesium methoxide. We have managed to increase the yield of targeted polyfluorosalicylic acids from good to quantitative. We have studied the tuberculostatic activity of polyfluorosalicylic acids. It has been found that minimum inhibitory concentration (MIC) of compounds is from 0.7 to 6.5 μg/mL depending on the structure.
BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME
-
, (2008/06/13)
The present invention provides a bicyclic triazolone derivative represented by the formula:J-Ar [wherein, J is and Ar is ], which has excellent selective weeding activity and weed killer containing the said bicyclic triazolone derivative.
