4,5-Difluoro-2-methoxybenzoic acid

Base Information

Chemical Name:4,5-Difluoro-2-methoxybenzoic acid
CAS No.:425702-18-7
Molecular Formula:C8H6F2O3
Molecular Weight:188.13
Hs Code.:2918990090
European Community (EC) Number:670-269-2
DSSTox Substance ID:DTXSID90476376
Wikidata:Q82307582
Mol file:425702-18-7.mol

Synonyms:4,5-DIFLUORO-2-METHOXYBENZOIC ACID;425702-18-7;4,5-DIFLUORO-2-METHOXYBENZOICACID;SCHEMBL1931203;DTXSID90476376;GMFHKGUQWAQEIW-UHFFFAOYSA-N;AMY41476;MFCD06660196;AKOS015956616;AS-19283;CS-0138868;EN300-1084745;Z1255424256

Suppliers and Price of 4,5-Difluoro-2-methoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,5-Difluoro-2-methoxybenzoicAcid
100mg
$ 75.00

SynQuest Laboratories
4,5-Difluoro-2-methoxybenzoic acid
5 g
$ 149.00

SynQuest Laboratories
4,5-Difluoro-2-methoxybenzoic acid
10 g
$ 274.00

Oakwood
4,5-Difluoro-2-methoxybenzoicacid
25g
$ 1400.00

Labseeker
4,5-difluoro-2-methoxybenzoicacid 95
5g
$ 417.00

Crysdot
4,5-Difluoro-2-methoxybenzoicacid 95+%
5g
$ 170.00

Crysdot
4,5-Difluoro-2-methoxybenzoicacid 95+%
25g
$ 560.00

Crysdot
4,5-Difluoro-2-methoxybenzoicacid 95+%
10g
$ 280.00

Crysdot
4,5-Difluoro-2-methoxybenzoicacid 95+%
1g
$ 50.00

Chemcia Scientific
4,5-Difluoro-2-methoxy-benzoicacid 95%
5 G
$ 330.00

Total 22 raw suppliers

Chemical Property of 4,5-Difluoro-2-methoxybenzoic acid

Chemical Property:

Boiling Point:282.6±35.0 °C(Predicted)
PKA:3.69±0.10(Predicted)
PSA：46.53000
Density:1.399±0.06 g/cm3(Predicted)
LogP:1.67160
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:188.02850037
Heavy Atom Count:13
Complexity:198

Purity/Quality:

97% ^*data from raw suppliers

4,5-Difluoro-2-methoxybenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1C(=O)O)F)F

Technology Process of 4,5-Difluoro-2-methoxybenzoic acid

There total 3 articles about 4,5-Difluoro-2-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 67-56-1
methanol

: 446-17-3
2,4,5-trifluorobenzoic acid

: 425702-18-7
2-methoxy-4,5-difluorobenzoic acid

Guidance literature:: methanol; With iodine; magnesium; In toluene; Reflux;

2,4,5-trifluorobenzoic acid; In toluene; at 85 - 90 ℃; for 2h;
DOI:10.1016/j.bmcl.2016.03.107