42580-78-9Relevant academic research and scientific papers
Synthesis and Photophysical Properties of 3-Amino-4-arylpyridin-2(1 H)-ones
Abramov, Anton A.,Chernenko, Sergey A.,Fisyuk, Alexander S.,Kostyuchenko, Anastasia S.,Shatsauskas, Anton L.
, p. 227 - 238 (2019/12/28)
A method has been developed for the preparation of oxazolo-[5,4- b ]pyridin-2(1 H)-ones based on the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides. Hydrolysis of oxazolo[5,4- b ]pyridin-2(1 H)-ones and the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides yielded 3-aminopyridin-2(1 H)-ones, including 4-aryl substituted derivatives in the series, for which effective phosphors with a quantum yield of up to 0.78 were detected. Photophysical properties of 3-aminopyridin-2(1 H)-ones were studied by UV and luminescence spectroscopy methods, and the relationship between their structure and photophysical properties was revealed.
FeCl3-promoted [3+3] cycloaddition: Efficient preparation of 1,2-dihydro-2-oxo-3-pyridinecarboxylate and 1,2-dihydro-2-oxo-3- pyridinecarboxamide derivatives
Li, Shuheng,Wang, Shaozhong
experimental part, p. 1875 - 1878 (2009/06/18)
(Chemical Equation Presented) A facile approach was developed on assembly of the 2-pyridone nucleus by ferric chloride promoted [3+3] cycloaddition in propionic acid. The tandem process involves cyclization of Michael adduct followed by aromatization. Thus, different substituted 1,2-dihydro-2-oxo-3- pyridinecarboxylate and 1,2-dihydro-2-oxo-3-pyridinecarboxamide derivatives were prepared in good yields from various enones with malonamic ester and malonamide, respectively.
A facile solid-phase synthesis of 3,4,6-trisubstituted-2-pyridones using sodium benzenesulfinate as a traceless linker
Li, Weiwei,Chen, Yu,Lam, Yulin
, p. 6545 - 6547 (2007/10/03)
A facile and traceless solid-phase synthesis of 3,4,6-trisubstituted-2- pyridones has been developed using polystyrene sodium benzenesulfinate resin. The chemistry is applicable to combinatorial library synthesis.
