4260-41-7 Usage
Uses
Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as an anticonvulsant medication for the treatment of epilepsy, neuropathic pain, and restless legs syndrome. It is effective in reducing the activity of certain chemicals in the brain, which helps alleviate neuropathic pain and provides relief from these conditions.
Used in Off-Label Treatments:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as an off-label treatment for anxiety, insomnia, and bipolar disorder. Its ability to reduce the activity of certain chemicals in the brain makes it a potential option for managing these conditions, although it is not officially approved for these uses.
Used in Pain Management:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as a pain management medication to alleviate neuropathic pain. It works by decreasing the release of pain-signaling neurotransmitters in the brain and spinal cord, providing relief from chronic pain conditions.
Used in Neurological Disorders:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as a medication for the treatment of neurological disorders such as epilepsy. Its anticonvulsant properties help control seizures and prevent their recurrence in patients with epilepsy.
Used in Sleep Disorders:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as a sleep aid for the treatment of insomnia. Its sedative effects can help improve sleep quality and duration in individuals struggling with sleep disorders.
Used in Mental Health:
2,4(1H,3H)-Pyrimidinedione, 3-(4-methylphenyl)is used as a medication for the treatment of mental health conditions such as anxiety and bipolar disorder. Its ability to reduce the activity of certain chemicals in the brain can help stabilize mood and alleviate anxiety symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 4260-41-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,6 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4260-41:
(6*4)+(5*2)+(4*6)+(3*0)+(2*4)+(1*1)=67
67 % 10 = 7
So 4260-41-7 is a valid CAS Registry Number.
4260-41-7Relevant academic research and scientific papers
Solid-phase synthesis of 4(1H)-quinolone and pyrimidine derivatives based on a new scaffold - Polymer-bound cyclic malonic acid ester
Huang, Xian,Liu, Zhanxiang
, p. 6731 - 6737 (2007/10/03)
An efficient method for the preparation of polymer-bound cyclic malonic acid ester starting from Merrifield resin has been developed. Reaction of the resin-bound cyclic malonic acid ester with triethyl orthoformate and subsequent double substitution with
STEREOCHEMICAL STUDIES 107; SATURATED HETEROCYCLES 111; PREPARATION OF URACILS VIA CYCLOREVERSION OF NORBORNENE-FUSED PYRIMIDINEDIONES
Bernath, Gabor,Stajer, Geza,Szabo, Angela E.,Szoeke-Molnar, Zsolt,Sohar, Pal,et al.
, p. 1921 - 1930 (2007/10/02)
From diexo-norbornane- and norbornene-azetidinones 5 and 6 with aryl isocyanates, N-arylcarbamoyl-substituted β-lactams (9 and 10) were prepared.The structures of the compounds were elucidated by IR, NMR spectroscopy and X-ray analysis, in comparison with saturated methylene-bridged quinazoline-2,4-diones (7a-b) prepared from norbornane-diexo-β-amino acid (1) with isocyanates and PPA.When heated with PPA, compounds 9 can be isomerized to 7.For preparation of the unsaturated compounds 8, the amino acid 2 was converted into the acid amides (13) and cyclized with 1,1'-carbonyl-diimidazole to tricyclic quinazoline-2,4-dione (8a-e), which decompose when heated, splitting off cyclopentadiene to yield 3-substituted uracils (14).
