42607-20-5

Usage

Uses

Used in Pharmaceutical Industry:
2,2'-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID is used as a starting material for the synthesis of 2-?substituted-?3-?acetyl-?thiazolidine-?4-?carbonyl-?amino acid derivatives. These derivatives exhibit antibacterial and antifungal properties, making them valuable in the development of new drugs and treatments for various infections.
Used in Chemical Synthesis:
2,2'-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID can be utilized as a building block in the synthesis of various complex organic molecules. Its unique structure and reactivity make it a versatile component in the creation of novel compounds with potential applications in different industries, such as pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 67-64-1 acetone 
• 52-90-4 L-Cysteine 

Downstream Products

• 95542-74-8 3-benzoyl-2,2-dimethyl-thiazolidine-4-carboxylic acid 
• 67180-02-3 (S)-((1R)-2-benzoyl-3,3-dimethyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-6-yl)-(4-benzyloxy-phenyl)-acetic acid benzyl ester 
• 67529-85-5 (R)-((1R)-2-benzoyl-3,3-dimethyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-6-yl)-(4-benzyloxy-phenyl)-acetic acid benzyl ester 
• 67149-40-0 (R)-((R)-3-benzoyl-2,2-dimethyl-thiazolidine-4-carbonylamino)-(4-benzyloxy-phenyl)-acetic acid benzyl ester 
• 67509-36-8 (R)-((4R)-3-benzoyl-5t-chloro-2,2-dimethyl-thiazolidine-4r-carbonylamino)-(4-benzyloxy-phenyl)-acetic acid benzyl ester 
• 67509-35-7 (R)-((4R)-3-benzoyl-5t-benzoyloxy-2,2-dimethyl-thiazolidine-4r-carbonylamino)-(4-benzyloxy-phenyl)-acetic acid benzyl ester 

Relevant academic research and scientific papers

[4R]-3-(Omega-AROYLPROPIONYL)-4-THIAZOLIDINECARBOXYLIC ACIDS AND ESTERS

This disclosure describes novel 4R!-3-(ω-aroylpropionyl)-4-thiazolidinecarboxylic acids and esters and the cationic salts thereof which are useful as hypotensive agents in mammals.

Substituted azetidin-2-one antibiotics

Monocyclic β-lactam antibiotics of the formula STR1 WHEREIN R is amino or acylamino, e.g., phenylacetylamino, phenylglycylamino and 2-[4-(3-amino-3-carboxypropoxy)phenyl]-2-hydroximinoacetylamino; R1 is H or ester forming group; R2 is H, --OCH3, --SCH3, or --CH3 ; and R3 is H or acetoxy; are useful antibacterials for controlling β-lactamase producing gram-negative bacteria and other pathogens. Intermediates useful in the preparation of the antibiotics and a novel process for preparing 4α-acetoxy substituted azetidin-2-ones are provided.