42717-06-6

Upstream product

• 100956-30-7 ethyl 2-((1H-indol-3-yl)methyl)-3-oxobutanoate 
• 5379-97-5 acetylamino-indol-3-ylmethyl-malonic acid diethyl ester 
• 64-17-5 ethanol 
• 1218-34-4 N-acetyl-DL-tryptophan 
• 68262-53-3 N-Acetyl-2,3-dihydro-Trp-OEt 
• 108-24-7 acetic anhydride 
• 6519-66-0 DL-tryptophan ethyl ester 
• 6519-67-1 DL-tryptophan ethyl ester hydrochloride 
• 75-36-5 acetyl chloride 
• 138742-45-7 ethyl 2-acetamido-4-bromopent-4-enoate 
• 191171-55-8 2-anilineboronic acid pinacol ester 
• 154048-76-7 2-Acetylamino-5-(tert-butyl-dimethyl-silanyl)-pent-4-ynoic acid ethyl ester 
• 154048-79-0 2-Acetylamino-3-[2-(tert-butyl-dimethyl-silanyl)-1H-indol-3-yl]-propionic acid ethyl ester 

Downstream Products

• 54-12-6 Trp 
• 1218-34-4 N-acetyl-DL-tryptophan 
• 6720-02-1 DL-tryptophanamide 
• 7303-49-3 DL-tryptophan methyl ester 
• 2382-80-1 N-acetyl-L-tryptophane ethyl ester 
• 92520-19-9 N-acetyl-D-tryptophan ethyl ester 
• 1218-34-4 N-AcTrp 
• 2280-01-5 N-acetyl-D-tryptophan 

Relevant academic research and scientific papers

Catalytic enantioselective synthesis of functionalized tropanes reveals novel inhibitors of hedgehog signaling

Dipolar cycloaddition: A highly efficient copper(I)-catalyzed enantioselective [3+2] cycloaddition reaction of 1,3-fused cyclic azomethine ylides and nitroalkenes has been developed. This method provides access to functionalized tropane scaffolds with several quaternary and tertiary stereocenters in a single step under mild reaction conditions. Copyright

Ir(iii)-Catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling for the synthesis of N-H indoles

Herein, an iridium(iii)-catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling of unprotected 2-alkenyl anilines is described. The developed method allows the synthesis of a variety of 3-substituted N-H indole scaffolds under undivided electrolytic conditions. Mechanistic studies suggest that the reaction proceeds through the electro-oxidation induced reductive elimination pathway.

Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-Nitrobenzofurans

A straight synthetic approach to fused polycyclic tropane scaffold formation through an asymmetric dearomatization cycloaddition process of 2-nitrobenzofurans with cyclic azomethine ylides was successfully developed. In the presence of a chiral copper com

Resolution of N-protected amino acid esters using whole cells of Candida parapsilosis ATCC 7330

Whole cells of Candida parapsilosis ATCC 7330 were used for the resolution of N-acetyl amino acid esters. Excellent enantioselectivities (E = 40 to >500) were achieved for the resolution of N-protected protein and non-protein amino acid esters giving good yields (28-50%) and high enantiomeric excesses (up to >99%) for both enantiomers.

ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE

This application discloses a composition comprising a malodor compound and an anti-odor ingredient effective for reducing the presence or production of malodor. The composition may be topically applied to a subject and is useful for cosmetic conditions, pharmaceutical indications, or other objectives.

A novel approach to Bz-substituted tryptophans via Pd-catalysed coupling/annulation

The Pd-catalysed preparation of bz-substituted tryptophans and their derivatives, starting from 2-iodoanilines and γ,δ-acetylenic amino acid derivatives, is reported.

AN EFFECTIVE DEHYDROGENATIONS OF INDOLINES TO INDOLES WITH COBALT(II) SCHIFF'S BASE COMPLEXES

Facile dehydrogenations of indolines to indoles were performed with the catalytic amount of bis(salicylidene)ethylenediaminatocobalt(II) and bis(3-methoxysalicylidene)ethylenediaminatocobalt(II) under mild conditions in 55-92percent yields.