4276-24-8Relevant academic research and scientific papers
The reaction of arynes with münchnones: Synthesis of isoindoles and azaisoindoles
Lopchuk, Justin M.,Gribble, Gordon W.
, p. 2809 - 2812 (2014/05/06)
Arynes derived from silyltriflate precursors undergo a smooth 1,3-dipolar cycloaddition with münchnones to furnish isoindoles and azaisoindoles in moderate to high yields. Modification of the fluoride source, solvent, and temperature allows for the selective generation of either isoindoles or benzanthracenimines, the latter of which serve as precursors to polycyclic aromatic hydrocarbons.
Integrated catalytic C-H transformations for one-pot synthesis of 1-arylisoindoles from isoindolines via palladium-catalyzed dehydrogenation followed by C-H arylation
Ohmura, Toshimichi,Kijima, Akihito,Suginome, Michinori
, p. 1238 - 1241 (2011/05/03)
A one-pot conversion of isoindolines to 1-arylisoindoles was established from palladium-catalyzed cascade C-H transformations, that is, the dehydrogenation of isoindolines to give isoindoles, with subsequent C-H arylation of the isoindoles.(Figure Presented)
