42763-00-8

Upstream product

• 108-94-1 cyclohexanone 
• 762-04-9 phosphonic acid diethyl ester 
• 110-89-4 piperidine 
• 36240-43-4 diethyl 1-(trimethylsiloxy)-1-cyclohexylphosphonate 
• 122-52-1 triethyl phosphite 
• 1474-78-8 triethyl phosphonoformate 
• 762-04-9 Diethyl phosphonate 
• 7413-09-4 Cyclohexyl-phosphonic acid diethyl ester 
• 108-93-0 cyclohexanol 
• 109-73-9 N-butylamine 

Downstream Products

• 91695-22-6 (1-Acetoxy-cyclohexyl)-phosphonsaeure-diaethylester 
• 51761-46-7 Methanesulfonic acid 1-(diethoxy-phosphoryl)-cyclohexyl ester 
• 85166-82-1 Methanesulfinic acid 1-(diethoxy-phosphoryl)-cyclohexyl ester 

Relevant academic research and scientific papers

Synthesis, structure, and hydrophosphorylation of π-complexes of hexacarbonyltungsten(0) with cyclohexanone, cyclohexanethione, and N-cyclohexylideneaniline

New carbonyl π-complexes of tungsten(0) with cyclohexanone, cyclohexanethione, and N-cyclohexylideneaniline were synthesized. Geometric and electronic parameters of the ligands, as well as energy parameters of the complex formation process, were determine

CeCl3?7H2O-catalysed hydrophosphonylation of aldehydes and ketones: An expeditious route to α-hydroxyphosphonates under solvent-free conditions

A cerium(III) chloride-catalysed expeditious synthesis of α-hydroxyphosphonates via a modified Abramov synthetic protocol has been developed. The scope of the current protocol is broad, with a range of aromatic, α,β-unsaturated and heterocyclic aldehydes

A simple heterogeneous catalyst for phosphite addition on carbonyl groups

A cheap and easily recoverable heterogeneous catalyst could efficiently trigger C-P bond formation by selective addition of phosphites to the carbonyl group of aldehydes and ketones. The reactions afford the desired products in good to excellent yields an

C-H hydroxylation of phosphonates with oxygen in [bmIm]OH to produce quaternary α-hydroxy phosphonates

A highly efficient and mild [bmIm]OH-catalyzed α-hydroxylation of phosphonates using O2 as the oxygen source is described. The employment of ionic liquid under mild reaction conditions makes this transformation green and practical. Especially, this reaction provided a novel and convenient methodology for the construction of quaternary α-hydroxy phosphonates.

The catalytic aerobic synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds

A highly efficient Cu-catalyzed direct hydroxylation of phosphonate compounds has been developed. This transformation provides a powerful method for the synthesis of quaternary α-hydroxy phosphonates in good yields. The direct transformation process, regiospecific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.

Synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds

It was found for the first time that Cs2CO3 serves as highly efficient catalyst for the direct hydroxylation reactions of phosphonates under mild conditions. This reaction provides an efficient approach to quaternary α-hydroxy phosph

Syntheses of bimetallic lanthanide bis(amido) complexes stabilized by bridged bis(guanidinate) ligands and their catalytic activity toward the hydrophosphonylation reaction of aldehydes and ketones

A series of bimetallic lanthanide bis(amido) complexes stabilized by bridged bis(guanidinate) ligands {[(Me3Si)2N]2Ln[(RN)2-CN(CH2)2]}2 [R= i Pr, Ln=Sm (1), Yb (2), Y

Lanthanide anilido complexes: Synthesis, characterization, and use as highly efficient catalysts for hydrophosphonylation of aldehydes and unactivated ketones

Lanthanide anilido complexes stabilized by the 2,6-diisopropylanilido ligand have been synthesized and characterized, and their catalytic activity for hydrophosphonylation reaction was explored. A reaction of anhydrous LnCl 3 with 5 equivalents

N -BuLi as a highly efficient precatalyst for hydrophosphonylation of aldehydes and unactivated ketones

It was found for the first time that organic alkali metal compounds serve as highly efficient precatalysts for the hydrophosphonylation reactions of aldehydes and unactivated ketones with dialkyl phosphite under mild conditions. For ketone substrates, a reversible reaction was observed, and the influence of catalyst loading and reaction temperature on the reaction equilibrium was studied in detail. Overall, the hydrophosphonylation reactions catalyzed by 0.1 mol % n-BuLi were completed within 5 min for a broad range of substrates and generated a series of α-hydroxy phosphonates in high yields.

Synthesis and characterization of amidate rare-earth metal amides and their catalytic activities toward hydrophosphonylation of aldehydes and unactivated ketones

Two novel amidate rare-earth metal amides Ln[N(SiMe3)2](κ2-L1)2(THF) (L1 = C6H5C(O)NC6H3(iPr)2) (Ln = Yb (1), Y (2)) were p