4278-87-9

Basic information

• Product Name: dicyclohexylidenehydrazine
• Synonyms: Cyclohexanone, cyclohexylidenehydrazone
• CAS NO: 4278-87-9
• Molecular Formula: C₁₂H₂₀N₂
• Molecular Weight: 192.3006
• Mol File: 4278-87-9.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 292.6°C at 760 mmHg
• Flash Point: 122.6°C
• Density: 1.07g/cm³
• Vapor Pressure: 0.00318mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: dicyclohexylidenehydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: dicyclohexylidenehydrazine(4278-87-9)
• EPA Substance Registry System: dicyclohexylidenehydrazine(4278-87-9)

Safety Data

• Hazardous Substances Data: 4278-87-9(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 108-93-0 cyclohexanol 
• 5351-77-9 cyclohexanone thiosemicarbazone 
• 2407-94-5 1,1'-dihydroxycyclohexyl peroxide 
• 176964-67-3 cyclohexanone 4-(3-hydroxypropyl)-4-methylsemicarbazone 
• 1589-61-3 cyclohexanone semicarbazone 
• 176964-70-8 5-Methyl-1,7-dioxa-5,14,15-triaza-dispiro[5.1.5.2]pentadec-14-ene 
• 1122-60-7 1-nitrocyclohexane 
• 13858-85-0 cyclohexanone O-methyloxime 
• 6156-08-7 cyclohexanone hydrazone 

Downstream Products

• 1589-62-4 cyclohexanone (2,4-dinitrophenyl)hydrazone 
• 108-91-8 cyclohexylamine 
• 79692-80-1 1,1,2-trichloro-2-(1-cyclohexenyl)ethane 
• 79692-81-2 1-(1,1,2,2-Tetrachloro-ethyl)-cyclohexene 
• 79692-82-3 1-(1,1,2,2-Tetrabromo-ethyl)-cyclohexene 
• 79692-79-8 1-(1-cyclohexenylazo)cyclohexanol 
• 102310-16-7 bis-[2-(2-methoxycarbonyl-ethyl)-cyclohexylidene]-hydrazine 
• 4359-62-0 N,N'-dicyclohexylhydrazine 
• 22122-96-9 3,4-Tetramethylen-5,5-pentamethylenpyrazolin 
• 57908-42-6 α,α'-dichloroazo compound 
• 26727-32-2 2,3,4,5,6,7,8,9-octahydro-1H-carbazole 
• 109127-31-3 2'-formyl-2',3'a,4',5',6',7'-hexahydro-spiro[cyclohexane-1,3'-indazole] 
• 1821-36-9 N-phenyl-2-cyclohexylamine 
• 101-83-7 N-cyclohexyl-cyclohexanamine 

Relevant articles and documents

Studies on isocyanides and related compounds; a facile synthesis of 4-phenyl-1-(2H)phthalazinone-2-alkanoic acid amides

A convenient synthesis of the title compounds by means of the Ugi four-component condensation (Ugi 4-CC) is reported. The reaction between acetaldehyde azine (3a), 2-benzoylbenzoic acid (4), and cyclohexyl isocyanide (5) spontaneously afforded N-cyclohexy

Metal-free and fecl3-catalyzed synthesis of azines and 3,5-diphenyl-1H-pyrazole from hydrazones and/or ketones monitored by high resolution ESI+-MS

9-Fluorenone azine 2a or benzophenone azine 2b have been synthesized, respectively, by treatment of 9-fluorenone hydrazone la or benzophenone hydrazone lb with FeCl3 Lewis acid catalyst in CHCb. Treatment of la and lb with FeCb affords the asymmetrical azine l-(diphenylmethylene)-2-(9H-fluoren-9-ylidene)hydrazine 2c. l,3-Diphenyl-2-propenone 3 reacts with hydrazine to produce l-((E)-l,3-diphenylallylidene)hydrazine 3a. Under prolonged heating, 3a undergoes a cyclization to yield 3,5-diphenyl-lH-pyrazoIe 4. Chalcone 3 reacts with la or lb to produce a mixture of 4 and 2a or 4 and 2b, respectively. The reaction of cyclohexanone 5 with hydrazine leads to the formation of 1,2-dicyclohexylidene hydrazine 6. Ketone 5 reacts with la or lb to give the asymmetrical azine product 6a or 6b, respectively. The progress of the reactions has been monitored by electrospray ionization mass spectrometry (ESI-MS), and the compounds have been characterized by elemental analyses, IR,1H,13C and DEPT-135 NMR spectroscopy and also by high resolution ESI+-MS.

Azines from one-pot reaction of thiosemicarbazones

Thermolysis and/or microwave irradiation of thiosemicarbazones gave the corresponding isothiocyanates, which on addition of either activated nitriles or aldehydes furnished various types of azines. The mechanism was discussed. The structures of products were proved by MS, IR, NMR, and elemental analyses (Image presented).