6156-08-7

Basic information

• Product Name: Cyclohexanone hydrazone
• Synonyms: Cyclohexanone hydrazone
• CAS NO: 6156-08-7
• Molecular Formula: C₆H₁₂N₂
• Molecular Weight: 0
• Mol File: 6156-08-7.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexanone hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone hydrazone(6156-08-7)
• EPA Substance Registry System: Cyclohexanone hydrazone(6156-08-7)

Safety Data

• Hazardous Substances Data: 6156-08-7(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 10424-93-8 N'-cyclohexylidene-N,N-dimethyl-hydrazine 
• 74105-60-5 (9H-fluoren-9-yl)methyl 2-cyclohexylidenehydrazinecarboxylate 

Downstream Products

• 2044-08-8 1-bromocyclohex-1-ene 
• 17497-53-9 1-iodo-1-cyclohexene 
• 29443-47-8 1,1-diiodocyclohexane 
• 10489-97-1 dibromo-cyclohexane 
• 6498-34-6 cyclohexylhydrazine 
• 108-94-1 cyclohexanone 
• 110-83-8 cyclohexene 
• 80484-21-5 3-(1-Acetoxycyclohexyl)propannitril 
• 110-82-7 cyclohexane 
• 108-93-0 cyclohexanol 
• 2412-73-9 benzoic acid cyclohexyl ester 
• 1821-36-9 N-phenyl-2-cyclohexylamine 
• 1256373-29-1 (1Z)-3-(3-bromo-4-fluorophenyl)-N'-cyclohexylidene-3-hydroxypropanehydrazonamide 
• 931-57-7 1-methoxy-cyclohex-1-ene 

Relevant articles and documents

Ruthenium catalyzed β-selective alkylation of vinylpyridines with aldehydes/ketonesviaN2H4mediated deoxygenative couplings

Umpolung (polarity reversal) tactics of aldehydes/ketones have greatly broadened carbonyl chemistry by enabling transformations with electrophilic reagents and deoxygenative functionalizations. Herein, we report the first ruthenium-catalyzed β-selective alkylation of vinylpyridines with both naturally abundant aromatic and aliphatic aldehyde/ketonesviaN2H4mediated deoxygenative couplings. Compared with one-electron umpolung of carbonyls to alcohols, this two-electron umpolung strategy realized reductive deoxygenation targets, which were not only applicable to the regioselective alkylation of a broad range of 2/4-alkene substituted pyridines, but also amenable to challenging 3-vinyl and steric-embedded internal pyridines as well as their analogous heterocyclic structures.

Sequential Suzuki-Miyaura Coupling/Lewis Acid-Catalyzed Cyclization: An Entry to Functionalized Cycloalkane-Fused Naphthalenes

Functionalized angular cycloalkane-fused naphthalenes were prepared using a two-step process involving a Pd-catalyzed Suzuki-Miyaura coupling of aryl pinacol boronates and vinyl triflates followed by a boron trifluoride etherate-catalyzed cycloaromatization.

Umpolung of Carbonyl Groups as Alkyl Organometallic Reagent Surrogates for Palladium-Catalyzed Allylic Alkylation

Palladium-catalyzed allylic alkylation of nonstabilized carbon nucleophiles is difficult and remains a major challenge. Reported here is a highly chemo- and regioselective direct palladium-catalyzed C-allylation of hydrazones, generated from carbonyls, as a source of umpolung unstabilized alkyl carbanions and surrogates of alkyl organometallic reagents. Contrary to classical allylation techniques, this umpolung reaction utilizes hydrazones prepared not only from aryl aldehydes but also from alkyl aldehydes and ketones as renewable feedstocks. This strategy complements the palladium-catalyzed coupling of unstabilized nucleophiles with allylic electrophiles by providing an efficient and selective catalytic alternative to the traditional use of highly reactive alkyl organometallic reagents.