427895-11-2

Upstream product

• 59020-10-9 3-(tributylstannyl)pyridine 
• 427895-03-2 tert-butyl-2-[2-(4-oxo-4H-benzo[d][1,2,3]-triazin-3-ylethyl)]-3-(4-bromo-phenylthio)propionate 
• 427895-01-0 tert-butyl-2-carboxymethyl-3-(4-bromophenylthio) propionate 
• 427895-02-1 tert-butyl-2-(2-hydroxy-ethyl)-3-(4-bromophenylthio) propionate 
• 134292-57-2 tert-butyl-2-methoxycarbonylmethyl acrylate 
• 253443-11-7 3-(tert-butoxycarbonyl)but-3-enoic acid 
• 106-53-6 para-bromobenzenethiol 
• 7338-27-4 4-methoxy-2-methylene-4-oxobutanoic acid 
• 97-65-4 2-methylenesuccinic acid 

Downstream Products

• 427895-12-3 N-allyloxy-2-[2-(4-oxo-4-benzo[d][1,2,3]triazin-3-ylethyl)]-3-(4-pyridin-3-ylphenylthio) propionamide 
• 253442-19-2 2-[2-(4-oxo-4-benzo[d][1,2,3]triazin-3-ylethyl)]-3-(4-pyridin-3-ylphenylthio) propionic acid 

Relevant academic research and scientific papers

Solid-phase synthesis of α-substituted 3-bisarylthio N-hydroxy propionamides as specific MMP Inhibitors

A novel series of potent and specific MMP-2,3,9,13 inhibitors has been obtained by modulation on solid phase by α and aryl substitutions on 3-arylthio-N-hydroxy-propionamides starting from itaconic acid.