4280-88-0Relevant academic research and scientific papers
Stereoselective thia-Michael 1,4-Addition to Acyclic 2,4-Dienones and 2-En-4-ynones
Kowalczyk, Rafa?,Boratyński, Przemys?aw J.
, p. 1289 - 1295 (2016)
Organocatalyzed highly stereoselective 1,4-thia-Michael addition of mercaptans to linear 2,4-dienones and 2-en-4-ynones was developed using Cinchona alkaloid-based squaramides. Application of only 0.5-1 mol % loading afforded products in up to 98:2 e.r. and above 99:1 after a single recrystallization. The adducts of allyl mercaptan can be conveniently further transformed to new chiral 2-substituted 2,5-dihydrothiophenes by ring-closing metathesis.
Ultrasound-promoted synthesis of 1,5-diarylpenta-2,4-dien-1-ones catalyzed by activated barium hydroxide
Xin, Ying,Zang, Zhi-He,Chen, Feng-Lei
experimental part, p. 4062 - 4068 (2009/12/24)
1,5-Diarylpenta-2,4-dien-1-ones were synthesized with ultrasound irradiation in the presence of activated barium hydroxide as catalyst. Compared to conventional methods, the present methodology offers several advantages such as excellent yields, simple procedure, short reaction times, and milder conditions.
