428439-26-3Relevant academic research and scientific papers
A facile total synthesis of ent-17β-estradiol and structurally related analogues
Cai, Zu Yun,Covey, Douglas F.
, p. 351 - 359 (2008/02/04)
A facile six-step synthesis (15.2% yield) of ent-17β-estradiol from readily accessible precursors is described. The preparation of analogues with 2-alkyl substituents, double bond unsaturation in the C-ring, a cis C,D-ring fusion and modified substituents at C17 is also reported.
Cytoprotective polycyclic compounds
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, (2008/06/13)
The present invention is generally directed to novel enantiomeric estrogen derivatives, some of which may have one or more unsaturated bonds in conjugation with the terminal or A-ring of the structure, which have cytoprotective activity. The present inven
