428506-23-4

Upstream product

• 288391-05-9 5'-O-(4,4'-dimethoxytrityl)-3'-deoxythymidine-3'-sulfamoyl-[3'(N)->5'(O)]-3'-O-(tert-butyldimethylsilyl)thymidine 
• 143526-94-7 3'-amino-5'-(4,4'-dimethoxytrityl)-3'-deoxythymidine 
• 288391-04-8 4-nitrophenyl 5'-O-(4,4'-dimethoxytrityl)-3'-deoxythymidine-3'-sulfamate 
• 21090-30-2 3'-O-acetylthymidine 
• 919367-37-6 acetic acid 2-{[2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]sulfamoyloxymethyl}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Crystal structure and photochemical behavior in solution of the 3′-N-sulfamate analogue of thymidylyl(3′-5′)thymidine

The 3′-N-sulfamate analogue of thymidylyl(3′-5′)thymidine (TnsoT, 1) exhibits a preference for a C3′-endo conformation in the solution and solid states. Its photochemical behavior in solution is compared to that of its natural counterpart, thymidylyl(3′-5

Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNA

A novel synthetic route for the preparation of sulfamide- and 3′-N-sulfamate-modified dinucleosides has been developed. The synthesis utilises 4-nitrophenyl chlorosulfate to prepare 4-nitrophenyl 3′- or 5′-sulfamates (e.g.,18 and 27), which couple smoothl

Replacement of the phosphodiester linkage in dna with sulfamide and 3'- N-sulfamate groups

Replacing phosphodiester linkages in DNA with neutral 3'-N-sulfamate groups has little effect on the binding affinity for complementary DNA or RNA, whereas incorporation of sulfamide groups into DNA results in considerable destabilisation of isosequential