428510-08-1

Basic information

• Product Name: Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)
• Synonyms: Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)
• CAS NO: 428510-08-1
• Molecular Formula: C10H17NO4
• Molecular Weight: 215.24628
• Product Categories: ALCOHOL
• Mol File: 428510-08-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)(428510-08-1)
• EPA Substance Registry System: Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)(428510-08-1)

Safety Data

• Hazardous Substances Data: 428510-08-1(Hazardous Substances Data)

Upstream product

• 22102-92-7 hexanoic acid hydroxysuccinimide ester 
• 92754-75-1 (2S,3R)-2-<(benzyloxycarbonyl)amino>-3-hydroxy-4-butanolide 
• 75266-39-6 methyl (S)-2-<<(benzyloxy)carbonyl>amino>-4-(methylsulfinyl)butanoate 
• 75266-40-9 N-benzyloxycarbonyl-L-α-vinylglycine methyl ester 
• 56762-93-7 methyl (S)-2-(benzyloxycarbonylamino)-4-methylmercaptobutanoate 

Relevant articles and documents

Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

The quorum sensing mechanism in Gram-negative bacteria uses small intercellular signal molecules, N-acyl-homoserine lactones (AHLs), to control transcription of specific genes in relation to population density. In this communication, we describe the parallel synthesis of new AHL analogues, in which substituents have been introduced into the 3- and 4-positions of the lactone ring. These analogues have been screened for their ability to activate and inhibit a Vibrio fischeri LuxI/LuxR-derived quorum sensing reporter system.