42865-19-0

Usage

Uses

Used in Polymer and Resin Production:
2-Bromoethyl isocyanate is used as a key component in the production of various polymers and resins. Its reactivity allows for the creation of a wide range of materials with diverse properties, making it valuable in this industry.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-Bromoethyl isocyanate serves as an essential intermediate in the synthesis of various drugs. Its ability to introduce isocyanate functional groups into organic molecules is crucial for the development of new medicinal compounds.
Used in Agricultural Chemical Synthesis:
2-Bromoethyl isocyanate is also utilized in the synthesis of agricultural chemicals, where its reactivity contributes to the development of effective products for crop protection and enhancement of agricultural yields.
Used as a Reagent in Chemical Reactions:
Due to its highly reactive nature, 2-Bromoethyl isocyanate is employed as a reagent in various chemical reactions. It is particularly useful for introducing isocyanate functional groups into organic molecules, which can be vital for the synthesis of specific chemical compounds.

InChI:InChI=1/C3H4BrNO/c4-1-2-5-3-6/h1-2H2

Upstream product

• 15486-96-1 3-Bromopropionyl chloride 
• 20236-50-4 silver (I) nitro cyanamide 
• 106-93-4 ethylene dibromide 

Downstream Products

• 100711-91-9 N-(2-bromo-ethyl)-N'-[1]naphthyl-urea 
• 52727-44-3 2,3-dihydro-5H-oxazolo<2,3-b>quinazolin-5-one 
• 497262-60-9 (2-bromo-ethyl)-thiocarbamic acid S-[2-(carbamoylmethyl-carbamoyl)-phenyl] ester 
• 443882-52-8 (2-bromo-ethyl)-thiocarbamic acid S-[2-(1-carbamoyl-ethylcarbamoyl)-phenyl] ester 
• 443882-51-7 (2-bromo-ethyl)-thiocarbamic acid S-[2-(2-carbamoyl-ethylcarbamoyl)-phenyl] ester 
• 631905-84-5 4-[4'-methoxy-6'-methyl-2'-(2-oxo-imidazolidin-1-yl)-biphenyl-3-sulfonyl]-5-methylsulfanyl-thiophene-2-carboxamidine trifluoroacetate 
• 105092-80-6 N-[p-bis(β-bromoethyl)aminophenyl]-N'-(β'-bromoethyl)urea 
• 916048-00-5 benzyl 5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1(2H)-carboxylate 
• 1017535-86-2 17-O-[N-(2-bromoethyl)carbamoyl]latrunculin A 
• 1039454-98-2 C₁₂H₁₀N₂O₄ 
• 1346771-61-6 C₁₇H₂₂BrN₃O₄S 
• 1332857-09-6 2-(2'-bromoethyl)-4-benzyl-1,2,4-thiadiazolidine-3,5-dione 
• 1449741-72-3 N₁-((5S,5aS,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydro[1,3]dioxolo[4',5':4,5]benzo[f]isobenzofuran-5-yl)-4-((((2-bromoethyl)amino)carbonyl)amino)benzamide 

Relevant academic research and scientific papers

Alkylation of Nitrocyanamide. A New Synthesis of Isocyanates

Thirteen alkyl halides (primary, secondary, and tertiary aliphatic including alicyclic, aralkyl, and heteroalkyl systems) and certain non-vicinal dihalides on treatment with silver nitrocyanamide are converted into the corresponding isocyanates (63-95percent).Intermediate alkylnitrocyanamides, spectroscopically detected, thermolysed (-20-80 deg C) to the expected isocyanates.In certain examples silver nitrocyanamide is generated in situ from sodium nitrocyanamide and silver nitrate.Silver nitrocyanamide does not react with cyclopropyl bromide, acetyl chloride, toluene-p-sulphonyl chloride, phenacyl bromide and 2-bromomethyldioxolane (27), and the ethylene acetal (28) of 1-bromo-4-iodopentacyclo-nonan-9-one.Silver nitrocyanamide reacts with 4,6-bis(bromomethyl)-3,7-dimethyl-1,5-diazabicyclo3.3.0)octane-2,8-dione (26), to give an intractable mixture.Vicinal dihalides give erratic results without detectable formation of vicinal di-isocyanates: unisolated 2-bromoethyl isocyanate (tentative assignment) has been detected in a product mixture from ethylene dibromide; an expected rearrangement during the reaction with 1,2-dibromocyclobutane, brought about the formation of 4-bromobut-3-enyl isocyanate isolated as ethyl 4-bromobut-3-enylcarbamate in low yield; and 1,2-dibromocyclohexane gives 2-bromocyclohexyl isocyanate isolated as ethyl N-(2-bromocyclohexyl)-carbamate in low yield.