51243-37-9Relevant academic research and scientific papers
METHOD FOR PRODUCING TRIAZOLIDINEDIONE COMPOUND
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Paragraph 0079-0080, (2021/08/20)
Provided is a method for industrially producing a triazolidinedione compound at a high purity and a high yield. A precipitation step for preparing a solution that contains a triazolidinedione compound represented by formula (1) and precipitating the triaz
1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF
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Paragraph 0362-0364, (2020/03/05)
The present invention relates to 1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole derivative compounds and uses thereof. In particular, compounds of the invention have antibacterial activity and/or are capable of re-sensitizing methicillin-resistant Staphylococcus aureus to a P-lactam antibiotic or a combination of a P-lactam antibiotic and a P-lactamase inhibitor. The present invention also relates to a method for producing and using said compounds.
Process for preparing enantiomerically pure indolopyrinidines
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Page/Page column 54, (2009/09/26)
The invention relates to a novel process for the preparation of pharmacologically interesting indolopyridine derivatives containing tetracyclic tetrahydro-?-carboline-hydantoines linked to a basic side chain and the corresponding salts, which can be used as Eg5 inhibitor, with very high overall chemical yield and enantiomeric purity.
INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5 )
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Page/Page column 75, (2009/04/25)
Compounds of formula (I), in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity.
BENZOTHIENOPYRIDINES FOR USE AS INHIBITORS OF EG5 KINESIN
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Page/Page column 26, (2008/06/13)
Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
