428830-45-9 Usage
Molecular Structure
The compound is made up of a nitrobenzyl group, a propylsulfonyl group, and a piperazine ring.
Functional Groups
Contains a nitro group (-NO2), a sulfonyl group (-SO2), and a piperazine ring (a five-membered ring with two nitrogen atoms).
Chemical Properties
The compound exhibits reactivity due to the presence of the nitro and sulfonyl groups, making it suitable for further chemical reactions and modifications.
Pharmaceutical Applications
It is used as a pharmaceutical intermediate in the synthesis of various medications.
Drug Delivery and Release
The nitrobenzyl group is commonly used for drug delivery and release applications, contributing to the compound's potential use in drug development.
Pharmacological Activity
The propylsulfonyl group is often found in pharmacologically active compounds, indicating the potential for biological activity in 1-nitrobenzyl-4-propylsulfonyl piperazine.
Heterocyclic Compound
The piperazine ring is a heterocyclic compound, which is known for its diverse biological activities and presence in many pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 428830-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,8,8,3 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 428830-45:
(8*4)+(7*2)+(6*8)+(5*8)+(4*3)+(3*0)+(2*4)+(1*5)=159
159 % 10 = 9
So 428830-45-9 is a valid CAS Registry Number.
428830-45-9Relevant academic research and scientific papers
five Yuan fragrance heterocyclic structure containing the anti-hepatitis c compound and its preparation and use
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Paragraph 0046; 0052-0053, (2016/11/21)
The invention discloses an anti-HCV (hepatitis C) compound containing a five-membered heteroaromatic ring structure, as well as a preparation method and applications thereof. The compound has a structure shown as the formula I, the compound has excellent anti-HCV virus activity, can be used for preparing anti-HCV drugs, the prepared drugs can be applied by adopting oral administration, intravenous injection or intramuscular injection.
NOVEL COMPOUNDS - 644
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, (2010/09/05)
The invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5, R6 and L are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are useful in the treatment of hepatitis C virus.
HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C
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Page/Page column 31, (2009/04/25)
Use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in treating or alleviating HCV, formula (I): wherein R1, R2, R4, Y1, Y2, Y3, A, B and W are as defined in the specification.
