4290-72-6

Basic information

• Product Name: AKOS BBS-00005456
• Synonyms: ASISCHEM C35315;AURORA KA-5263;AKOS BBS-00005456;5,6-DIHYDRO-4H-PYRROLO[3,2,1-IJ]QUINOLINE-1,2-DIONE;AKOS VGY0016005;5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione(SALTDATA: FREE);4H-Pyrrolo[3,2,1-ij]quinoline-1,2-dione, 5,6-dihydro-
• CAS NO: 4290-72-6
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19
• Mol File: 4290-72-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 357.8°Cat760mmHg
• Flash Point: 173.5°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 2.67E-05mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: AKOS BBS-00005456(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS BBS-00005456(4290-72-6)
• EPA Substance Registry System: AKOS BBS-00005456(4290-72-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 4290-72-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H9NO2/c13-10-8-5-1-3-7-4-2-6-12(9(7)8)11(10)14/h1,3,5H,2,4,6H2

Upstream product

• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 79-37-8 oxalyl dichloride 
• 5840-01-7 5,6-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline 
• 201230-82-2 carbon monoxide 
• 924-44-7 glyoxylic acid ethyl ester 

Relevant articles and documents

Spiro[4H-pyran-3,3′-oxindoles] Derived from 1,2,3,4-Tetrahydroquinoline

Three-component reactions of 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione with malononitrile, or ethyl cyanoacetate, and cyclic six-membered or a five-membered 1,3-diketone, produce spiro[4H-pyran-3,3′-oxindoles].

Three-component synthesis of novel spiro[4H-pyran-3,3-oxindoles] using 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione

One-pot, three-component reactions of the tricyclic isatin 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione with variously substituted aryl cyanomethyl ketones and malononitrile, or ethyl cyanoacetate, generates spiro[4H-pyran-3,3-oxindoles], such as, 2-amino-2'-oxo-6-(phenyl)-5',6'-dihydro-2'H,4'H-spiro[pyran-4,1'-pyrrolo[3,2,1-ij]quinoline]-3,5-dicarbonitrile.

Hexahydrospiro-pyrazolo[3,4-b]pyridine-4,1′-pyrrolo[3,2,1-ij]quinolines Derived from 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione

The tricyclic isatin, 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione (1), reacts with a combination of an aryl cyanomethyl ketone 8 and a 5-amino-1-arylpyrazole 7 to generate spirocyclic products 9.