42951-71-3

Usage

Chemical Properties

Off-white solid

InChI:InChI=1/C8H6BrClN2/c1-4-6(3-11)8(10)12-5(2)7(4)9/h1-2H3

Upstream product

• 23819-87-6 5-bromo-2-hydroxy-4,6-dimethyl-nicotinonitrile 
• 769-28-8 3-Cyano-4,6-dimethyl-2(1H)-pyridon 
• 23819-87-6 5-bromo-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 

Downstream Products

• 113893-02-0 5-bromo-3-cyano-2-methoxy-4,6-dimethylpyridine 
• 63644-86-0 5-Bromo-3-cyano-4,6-dimethylpyridine 
• 42951-65-5 5-bromo-4,6-dimethyl-1⁽²⁾H-pyrazolo[3,4-b]pyridin-3-ylamine 
• 93350-07-3 Methyl 4,6-Dimethyl-5-phenylnicotinate 
• 93350-01-7 5-bromo-4,6-dimethylpyridine-3-carboxylic acid 

Relevant academic research and scientific papers

ROR NUCLEAR RECEPTOR MODULATORS

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.

Novel pyrazolo[3,4-b]pyridine derivatives: Synthesis, characterization, antimicrobial and antiproliferative profile

Three novel series of pyridine derivatives, namely Schiff's bases, 4-thiazolidinones and azetidin-2-ones bearing pyrazolo[3,4-b]pyridine moiety, have been synthesized. The chemical structures of the synthesized compounds were characterized. The compounds

2,4-diamino-5,6-disubstituted- and 5,6,7-trisubstituted 5-deazapteridines as insecticides

An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a 5-deazapteridine compound of the formula: STR1 wherein R1, R2, R3, R4, U, V, and W are as defined herein; agriculturally acceptable salts thereof; methods for using the same; and certain novel 5-deazapteridines per se.

A General Synthesis of 5-Arylnicotinates

Arylboronic acids have been found to couple efficiently with 5-bromonicotinates to yield 5-arylnicotinates.The reaction is considerably more sensitive to steric inhibition in the arylboronic acid component than in the pyridyl bromide 4.The dianion salt of the boronic acid is implicated as the reactive intermediate responsible for the facile coupling reaction.Pure arylboronic acids are best prepared by using triisopropyl borate as the transmetalating agent.