42951-91-7

Usage

Uses

1-(2-Chloroacetyl)-4-methylpiperazine HCl

Upstream product

• 109-01-3 1-methyl-piperazine 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 92897-32-0 2H,5H,-6,7-dihydrothiazolo<3,2-a>pyrimidin-3(2H)-one 
• 50398-09-9 N-methylpiperazine dihydrochloride 
• 262298-71-5 4-hydroxy-benzoic acid 2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl ester 
• 1613475-51-6 tert-butyl-N-[(1S,2R)-1-methyl-2-phenylcyclopropyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]carbamate 
• 1610862-15-1 benzyl 4-methoxy-3-(N-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)methylsulfonamido)benzoate 
• 94012-38-1 2-(4-Cyclohexanecarbonyl-piperazin-1-yl)-1-(4-methyl-piperazin-1-yl)-ethanone 
• 94012-35-8 1-(piperazin-1-ylacetyl)-4-methylpiperazine 
• 262299-33-2 piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-{4-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethoxycarbonyl]-phenyl} ester 
• 94012-34-7 1-Methyl-4-(4-benzylpiperazine-1-ylacetyl)piperazine 

Relevant academic research and scientific papers

REACTION OF CYCLIC THIOUREAS WITH CHLOROACYLPIPERAZINES

S-Alkylation products are formed in the reaction of tetrahydropyrimidine-2-thione and hexahydro-1,3-diazepine-2-thione with chloroacylpiperazines in dimethylformamide at room temperature; dihydrothiazolopyrimidine and tetrahydrothiazolo-diazepine systems are obtained in refluxing ethanol.It is shown that the S-alkyl derivatives are very readily converted to condensed systems.