429628-68-2Relevant academic research and scientific papers
Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties
De Vita, Daniela,Angeli, Andrea,Pandolfi, Fabiana,Bortolami, Martina,Costi, Roberta,Di Santo, Roberto,Suffredini, Elisabetta,Ceruso, Mariangela,Del Prete, Sonia,Capasso, Clemente,Scipione, Luigi,Supuran, Claudiu T.
, p. 798 - 804 (2017)
We discovered novel and selective sulfonamides/amides acting as inhibitors of the α-carbonic anhydrase (CA, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae (VchCA). This Gram-negative bacterium is the causative agent of cholera and colonises the
