Journal of Enzyme Inhibition and Medicinal Chemistry p. 798 - 804 (2017)
Update date:2022-08-05
Topics: Amides Sulfonamides Experimental Inhibition
De Vita, Daniela
Angeli, Andrea
Pandolfi, Fabiana
Bortolami, Martina
Costi, Roberta
Di Santo, Roberto
Suffredini, Elisabetta
Ceruso, Mariangela
Del Prete, Sonia
Capasso, Clemente
Scipione, Luigi
Supuran, Claudiu T.
We discovered novel and selective sulfonamides/amides acting as inhibitors of the α-carbonic anhydrase (CA, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae (VchCA). This Gram-negative bacterium is the causative agent of cholera and colonises the
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