4298-15-1 Usage
Uses
Used in Pharmaceutical Industry:
DESETHYL HYDROXY CHLOROQUINE is used as an antimalarial agent for treating malaria caused by Plasmodium species. Its application is based on its ability to inhibit the growth and reproduction of the malaria parasite within the host's red blood cells.
DESETHYL HYDROXY CHLOROQUINE is also used as an antirheumatic medication for managing symptoms of rheumatoid arthritis and other autoimmune diseases. Its application in this context is due to its immunomodulatory and anti-inflammatory effects, which help alleviate pain, swelling, and joint damage associated with these conditions.
Furthermore, DESETHYL HYDROXY CHLOROQUINE is used as a lupus erythematosus suppressant for treating systemic lupus erythematosus (SLE), an autoimmune disease that can cause widespread inflammation and damage to various organs. Its application in this area is attributed to its ability to suppress the immune system and reduce the severity of SLE symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 4298-15-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,9 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4298-15:
(6*4)+(5*2)+(4*9)+(3*8)+(2*1)+(1*5)=101
101 % 10 = 1
So 4298-15-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)
4298-15-1Relevant academic research and scientific papers
Preparation method of hydroxychloroquine impurity
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Paragraph 0056-0057; 0062-0063; 0068-0069; 0074-0075, (2020/08/22)
The invention discloses a preparation method of a hydroxychloroquine impurity. 4-amino-1-pentanol taken as a raw material undergoes a five-step reaction to realize synthesis of a hydroxychloroquine impurity VIII. The preparation method is reasonable in process design and high in operability, and industrial production can be realized; reagents used in the synthesis method are simple and easy to obtain; the purity of the hydroxychloroquine impurity obtained through the reaction can reach 98% or above, and the total yield can reach 20% or above. The hydroxychloroquine impurity prepared by the invention provides an important basis for scientific evaluation of quality, safety and efficiency of hydroxychloroquine.
