927-55-9

Basic information

• Product Name: 4-aminopentan-1-ol
• Synonyms: 4-aminopentan-1-ol;4-Amino-1-pentanol;Einecs 213-151-4;NSC 1095
• CAS NO: 927-55-9
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16282
• EINECS: 213-151-4
• Product Categories: Aliphatics;Amines;Miscellaneous Reagents
• Mol File: 927-55-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 32°C
• Boiling Point: 117-119°C/25 mm
• Flash Point: 59.4 °C
• Appearance: /
• Density: 0.915 g/cm³
• Vapor Pressure: 0.369mmHg at 25°C
• Refractive Index: 1.449
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• PKA: 15.12±0.10(Predicted)
• CAS DataBase Reference: 4-aminopentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aminopentan-1-ol(927-55-9)
• EPA Substance Registry System: 4-aminopentan-1-ol(927-55-9)

Safety Data

• Hazardous Substances Data: 927-55-9(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Low Melting Solid

InChI:InChI=1/C5H13NO/c1-5(6)3-2-4-7/h5,7H,2-4,6H2,1H3

Upstream product

• 57669-08-6 5-hydroxypentan-2-one oxime 
• 1071-73-4 5-Hydroxy-2-pentanone 
• 10312-37-5 methyl 4-nitropentanoate 
• 74-80-6 pentyl hydroperoxide 
• 4093-53-2 4-nitro-valeric acid ethyl ester 

Downstream Products

• 64992-33-2 N-(4-hydroxy-1-methyl-butyl)-phthalimide 
• 10500-64-8 4-(7-chloro-quinolin-4-ylamino)-pentan-1-ol 
• 4298-15-1 Cletoquine 
• 1356009-48-7 5-(2-(3-methyl-1H-1,2,4-triazol-1-yl)-5-nitrophenoxy)pentan-2-amine 
• 1356009-59-0 tert-butyl (5-(2-(3-methyl-1H-1,2,4-triazol-1-yl)-5-nitrophenoxy)pentan-2-yl)carbamate 
• 1356008-77-9 18-(2,4-difluorophenyl)-13-methyl-7-(3-methyl-1H-1,2,4-triazol-1-yl)-10,11,12,13,14,16,17,18-octahydro-3H-15,2-(azeno)-4,8-(metheno)cyciopenta[h][1,6,10,12]oxatriazacycloheptadecine 
• 1356010-60-0 N-(5-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)pentan-2-yl)-2-chloro-7-(2,4-difluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 
• 1356009-99-8 2-chloro-7-(2,4-difluorophenyl)-N-(5-(2-(3-methyl-1H-1,2,4-triazol-1-yl)-5-nitrophenoxy)pentan-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 
• 179412-96-5 tert-butyl (4-hydroxy-1-methylbutyl)carbamate 
• 804440-41-3 Benzilsaeure-({2-[aethyl-(4-chlor-1-methyl-butyl)-amino]-aethylester}) 
• 98131-27-2 Benzilsaeure-<<2--aethylester>> 
• 58554-66-8 N-(4-bromo-1-methyl-butyl)-phthalimide 
• 765-38-8 2-methyl-1-pyrrolidine 

Relevant articles and documents

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This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinoline or thioxanthenone (or similar) structure which function as autophagy inhibitors and/or histone deactylase inhibitors, and their use as therapeutics for the treatment of conditions characterized with aberrant autophagy activity and/or aberrant HDAC activity (e.g., cancer, pulmonary hypertension, diabetes, neurodegenerative disorders, aging, heart disease, rheumatoid arthritis, infectious diseases, conditions and symptoms caused by a viral infection (e.g., COVID-19)).

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