430-61-5Relevant academic research and scientific papers
1,1,2,2-Tetrafluoroethyl-N,N-dimethylamine: A new selective fluorinating agent
Petrov,Swearingen,Hong,Chris Petersen
, p. 25 - 31 (2007/10/03)
The title compound has been prepared in 96-98% yield by the reaction of tetrafluoroethylene and dimethylamine. 1,1,2,2-Tetrafluoroethyl-N,N-dimethylamine (1) is found to be an effective reagent for the conversion of alcohols into alkyl fluorides. Reaction of 1 and primary alcohols proceeds with high yield formation of the corresponding alkyl fluorides at elevated temperature. However, the reaction of secondary and tertiary alcohols rapidly takes place at 0-10°C, producing corresponding alkyl fluorides as major product along with some olefins.
Fluorination of Alkanes by Chlorine Trifluoride. Hydride Abstraction Mechanism
Brower, K. R.
, p. 798 - 802 (2007/10/02)
Addition of chlorine trifluoride to a solution of alkane in Freon or liquid carbon dioxide at -75 deg C gives good yields of monofluoroalkane along with difluoro- and trifluoroalkanes in amounts dependent on reactant proportions.The inorganic products are HF and ClF.The reaction is highly selective for 3 over 2 positions.Methane and hexamethylethane are unreactive.Neohexane fluorinates with rearrangement, but 2-fluoro-3,3-dimethylbutane exposed to the postreaction medium does not rearrange.A hydride abstraction mechanism is inferred.
The Generation of CF and an Investigation of the Products of Its Reaction with Alkenes
Rahman, M.,McKee, Michael L.,Shevlin, Philip B.
, p. 6296 - 6299 (2007/10/02)
The reaction of arc generated carbon atoms with CF4 at 77 K in the presence of alkene trapping agents results in the formation of fluorocyclopropanes and 1,1-difluoroalkanes.The fluorocyclopropanes are postulated to arise by addition of CF to the double bond generating a cyclopropyl radical which abstracts H.CF adds stereospecifically to olefins and gives both cis and trans fluorocyclopropanes with the trans generally predominating.The 1,1-difluoroalkanes are postulated to be the result of a 3CF2 reaction.In the presence of oxygen, the CF is oxidized to CO2, and the 3CF2 gives carbonyl fluoride.
