430-69-3Relevant articles and documents
Manufacturing method of [alpha],[alpha]-difluoroacetaldehyde
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Paragraph 0098; 0099; 0101; 0103; 0106; 0108; 0110; 0112, (2017/09/26)
The objective of the present invention is to provide a manufacturing method of [alpha],[alpha]-difluoroacetaldehyde capable of being industrially easily implemented without special equipment. The manufacturing method of [alpha],[alpha]-difluoroacetaldehyde or hydrate thereof or hemiacetal is characterized in that difluoroacetate represented by the general formula CF2HCOOR1[R1 represents an alkyl group or substituted alkyl group] reacts with tetrahydridoborate which serves as a hydride reducing agent in the presence of a protic solvent and alkali.