43007-35-8Relevant academic research and scientific papers
Synthesis and biological activities of N,N-dimethyl-2-propen-1-amine derivatives
Conti, R. De,Gimenez, S. M. N.,Haun, M.,Pilli, R. A.,Castro, S. L. De,Duran, N.
, p. 915 - 918 (2007/10/03)
The synthesis of several 3-(4'-bromo-4-yl)-3-(4-X-phenyl)-N,N-dimethyl-2-propen-1-amine derivatives is described.These compounds are potential trypanocide agents with relative low acute toxicities. the inhibition of growth of Escherichia coli by these drugs with different para-substitution on the phenyl moiety and their trypanocidal activities against epimastigote from Trypanosoma cruzi were investigated. - Keywords: Chagas's disease; trypanocide; Trypanosoma cruzi; aminopropene.
