43018-61-7

Basic information

• Product Name: 5-(DIMETHYLAMINO)PENTAN-2-ONE
• Synonyms: 5-DIMETHYLAMINOPENTANONE-2;5-(DIMETHYLAMINO)PENTAN-2-ONE;2-Pentanone, 5-(dimethylamino)- (9CI)
• CAS NO: 43018-61-7
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2
• Product Categories: ACETYLGROUP
• Mol File: 43018-61-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 172.5°C at 760 mmHg
• Flash Point: 45.5°C
• Appearance: /
• Density: 0.87g/cm³
• Vapor Pressure: 1.32mmHg at 25°C
• Refractive Index: 1.428
• PKA: 9.43±0.28(Predicted)
• CAS DataBase Reference: 5-(DIMETHYLAMINO)PENTAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(DIMETHYLAMINO)PENTAN-2-ONE(43018-61-7)
• EPA Substance Registry System: 5-(DIMETHYLAMINO)PENTAN-2-ONE(43018-61-7)

Safety Data

• Hazardous Substances Data: 43018-61-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 105, p. 6877, 1983 DOI: 10.1021/ja00361a023

InChI:InChI=1/C7H15NO/c1-7(9)5-4-6-8(2)3/h4-6H2,1-3H3

Upstream product

• 40065-16-5 2-(2-dimethylamino-ethyl)-acetoacetic acid ethyl ester 
• 3884-71-7 bromo-5-pentanone-2 
• 124-40-3 dimethyl amine 
• 75-05-8 acetonitrile 
• 1001-91-8 N,N-dimethylpent-4-enylamine 
• 5891-21-4 5-chloro-2-pentanone 
• 506-59-2 N,N-dimethylammonium chloride 

Downstream Products

• 25351-18-2 (4-oxopentyl)trimethylammonium iodide 
• 206062-77-3 5-dimethylamino-pentan-2-one oxime 
• 5843-07-2 Acetic acid N-(4-dimethylamino-1-methyl-butyl)-N'-isopropylidene-hydrazide 
• 189806-34-6 N-[3-(2-dimethylaminoethyl)-2-methyl-1H-indol-5-yl]-4-fluorobenzamide 

Relevant articles and documents

METHODS OF TREATING OR AMELIORATING THE SYMPTOMS OF COMMON COLD OR ALLERGIC RHINITIS WITH SEROTONIN 5-HT1F

This invention provides methods for the treatment or amelioration of the symptoms of the common cold or allergic rhinitis which comprises administering to a mammal in need thereof a serotonin 5-HT 1F agonist.

New serotonin 5-HT1F agonists

This invention provides novel 5-HT1Fagonists of formula where X, Y, Z,and R are defined in the specification, which are useful for the prevention and treatment of migraine and associated disorders.

Palladium-Catalyzed Oxidation of Amino Alkenes to Cyclic Imines or Enamines and Amino Ketones

Amino alkenes of the type CH2=CH(CH2)nNH2 (n = 3,4) are cyclized to pyrrolines or piperideines under ''Wacker process''conditions.Amino alkenes with a secondary amino group yield the corresponding cyclic enamines, while tertiary amino alkenes give amino ketones.