43036-06-2

Basic information

• Product Name: N-(2-CYANOETHYL)PYRROLE
• Synonyms: 1-(2-CYANOETHYL)PYRROLE;1-PYRROLEPROPIONITRILE;3-(1H-PYRROL-1-YL)PROPANENITRILE;3-(PYRROL-1-YL)PROPIONITRILE;N-(2-CYANOETHYL)PYRROLE;1H-Pyrrole-1-propanenitrile;Pyrrole-1-propionitrile;3-(pyrrol-1-yl)propiononitrile
• CAS NO: 43036-06-2
• Molecular Formula: C₇H₈N₂
• Molecular Weight: 120.15
• EINECS: 256-051-6
• Product Categories: AMINETERTIARY
• Mol File: 43036-06-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 132-133 °C10 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: clear slightly yellow to brown liquid
• Density: 1.048 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00846mmHg at 25°C
• Refractive Index: n20/D 1.51(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform
• PKA: -3.80±0.70(Predicted)
• CAS DataBase Reference: N-(2-CYANOETHYL)PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-CYANOETHYL)PYRROLE(43036-06-2)
• EPA Substance Registry System: N-(2-CYANOETHYL)PYRROLE(43036-06-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 43036-06-2(Hazardous Substances Data)

Usage

Chemical Properties

N-(2-CYANOETHYL)PYRROLE is clear slightly yellow to brown liquid

Uses

Different sources of media describe the Uses of 43036-06-2 differently. You can refer to the following data:
1. N-(2-CYANOETHYL)PYRROLE is used in the synthesis of 2-pyridines. It is also used in the preparation of indoles/pyrroles.
2. 1H-Pyrrole-1-propanenitrile is used in the synthesis of 2-pyridines. It is also used in the preparation of indoles/pyrroles.

InChI:InChI=1/C7H8N2/c8-4-3-7-9-5-1-2-6-9/h1-2,5-6H,3,7H2

Upstream product

• 542-76-7 3-Chloropropionitrile 
• 16199-06-7 potassium pyrrolide 
• 31164-08-6 3-(diallylamino)propanenitrile 
• 34583-60-3 p-CH₃C₆H₄-O₂SO-CH₂CH₂CN 
• 109-97-7 pyrrole 
• 107-13-1 acrylonitrile 

Downstream Products

• 1242419-83-5 C₁₆H₁₇N₃ 
• 1289675-82-6 3-(2-(2-oxo-4-phenylbut-3-ynoyl)-1H-pyrrol-1-yl)propanenitrile 
• 1415034-40-0 6-chloro-1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxamide 
• 1415034-39-7 1-(2,4-dichlorophenyl)-6-methyl-N-(piperidin-1-yl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxamide 
• 1415034-38-6 6-chloro-1-(2,4-dichlorophenyl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylic acid 
• 1415034-37-5 1-(2,4-dichlorophenyl)-6-methyl-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylic acid 
• 1415034-36-4 ethyl 6-chloro-1-(2,4-dichlorophenyl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylate 
• 1415034-35-3 ethyl 1-(2,4-dichlorophenyl)-6-methyl-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylate 
• 1415034-34-2 ethyl 1-(2,4-dichlorophenyl)-1,4-dihydropyrazolo[3,4-a]pyrrolizine-3-carboxylate 
• 63202-71-1 2-(4′-nitrophenyl)pyrrole 
• 1226779-94-7 C₁₆H₁₆N₂ 
• 1226779-96-9 C₁₆H₁₆N₂O 
• 1226779-97-0 C₁₇H₁₉N₃ 
• 1226779-92-5 C₁₅H₁₄N₂ 

Relevant articles and documents

Electrochemical polymerization of pyrrole containing TEMPO side chain on pt electrode and its electrochemical activity

Poly(4-(3-(pyrrol-1-yl)propionyloxy)-2,2,6,6-tetramethylpiperidin-1-yloxy) (PPy-TEMPO) electrode is prepared by electrochemical polymerization on Pt electrode in NaClO4-CH3CN solution. The electrocatalytic activity of PPy-TEMPO for benzyl alcohol in NaClO4-CH3CN solution is investigated by cyclic voltammetry and in situ FTIR. Results show that PPy-TEMPO electrode exhibits high electrocatalytic activity for benzyl alcohol oxidation in the presence of 2,6-lutidine as the base, as compared with the bare Pt electrode under the similar conditions. On the basis of in situ FTIR data, it shows that TEMPO is oxidized to its cation at the potential about 0.4 V, and benzyl alcohol is oxidized to benzaldehyde instead of benzoic acid. Further studies of preparative electrolysis experiments by constant current electrolysis are carried out to confirm the high conversion to benzaldehyde, and the results are in good agreement with those from in situ FTIR investigations.

Tricyclic pyrazoles: An efficient approach to cannabinoid analogues with a tricyclic framework incorporating the pyrrole and pyrazole moieties

In this paper we report the synthesis of some new cannabinoid analogues that share with rimonabant, a potent and selective CB1 antagonist, the 2,4-dichlorophenyl and piperidin-1-yl substituents on the pyrazole and amide nitrogens, respectively. The general synthesis involves the preparation of a cyclic ketone condensed with a pyrrole, followed by Claisen condensation with diethyl oxalate; from here, an aza-annulation reaction with a substituted hydrazine followed by an amidation step complete the synthesis. Georg Thieme Verlag Stuttgart.New York.

Novel amine-catalysed hydroalkoxylation reactions of activated alkenes and alkynes

Substoichiometric loadings of DBU catalyse the efficient 1,4-addition of alcohols and non-nucleophilic amines such as pyrrole to activated alkenes; the application of this methodology in a one-pot synthesis of a natural product, and as a novel strategy for the synthesis of mono-protected 1,3-carbonyl compounds is reported.