430430-57-2

Basic information

• Product Name: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate
• Synonyms: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate
• CAS NO: 430430-57-2
• Molecular Weight: 327.399
• Mol File: 430430-57-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate(430430-57-2)
• EPA Substance Registry System: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate(430430-57-2)

Safety Data

• Hazardous Substances Data: 430430-57-2(Hazardous Substances Data)

Usage

General Description

2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate is a synthetic chemical compound commonly used as a reagent in organic synthesis. It is a derivative of the compound methanesulfonic acid, and contains a 13-carbon backbone with three oxygen atoms and one nitrogen atom. The presence of the oxo and methyl groups in the compound provide it with unique properties that make it suitable for a variety of chemical reactions, including as a protecting group in organic synthesis. 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl methanesulfonate is commonly employed in the pharmaceutical and research industries for the production of various compounds and materials.

Upstream product

• 86520-52-7 2-[2-(2-azidoethoxy)ethoxy]ethanol 
• 6338-55-2 2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol 

Downstream Products

• 1292268-14-4 2,2-dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate 
• 1292268-15-5 t-butyl 20-azido-3,6,9,12,15,18-hexaoxaicosylcarbamate 
• 1292268-13-3 t-butyl 20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate 
• 1404111-67-6 tert-butyl N-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate 
• 1333880-60-6 tert-butyl (2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)carbamate 
• 932741-19-0 2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethanamine 
• 1355027-66-5 [2-(21-amino-3-oxo-7,10,13,16,19-pentaoxa-4-azahenicos-1-yl)-4-{[(4-{[(2,6-dimethylphenyl)carbamoyl]amino}phenyl)acetyl]amino}phenoxy]acetic acid trifluoroacetate 
• 1355027-79-0 tert-butyl [2-(2,2-dimethyl-4,24-dioxo-3,8,11,14,17,20-hexaoxa-5,23-diazahexacosan-26-yl)-4-{[(4-{[(2,6-dimethylphenyl)carbamoyl]amino}phenyl)acetyl]amino}phenoxy]acetate 
• 911209-07-9 tert-butyl N-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate 
• 189209-27-6 tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy] ethoxy]ethoxy]ethyl]carbamate 
• 1349193-24-3 N-[N₁-(8-tert-butoxycarbonylamino-3,6-dioxaoct-1-yl)-1,2,3-triazol-4-yl]methyl-N-[N₆-(benzyloxycarbonyl)adenin-9-ylacetyl]glycineethyl ester 
• 1349193-23-2 N-[N₁-(8-tert-butoxycarbonylamino-3,6-dioxaoct-1-yl)-1,2,3-triazol-4-yl]methyl-N-[N₄-(benzyloxycarbonyl)cytosin-1-ylacetyl]glycine ethyl ester 
• 1016274-47-7 C₃₇H₄₅F₃N₄O₉ 
• 880359-81-9 C₆₆H₁₀₃B₃N₈O₁₈ 

Relevant articles and documents

NOVEL AUTOPHAGY-TARGETING CHIMERA (AUTOTAC) COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING DISEASES THROUGH TARGET PROTEIN DEGRADATION COMPRISING SAME

The present invention relates to a novel AUTOTAC chimeric compound in which a new p62 ligand and a target-binding ligand are connected by a linker, a stereoisomer, hydrate, solvate or prodrug thereof, and a pharmaceutical or food composition for the prevention or treatment of diseases by degrading the target protein including the same as an active ingredient. They can target specific proteins to adjust their concentrations, and can also deliver drugs and other small molecule compounds to lysosomes. The AUTOTAC chimeric compound according to the present invention can be usefully used as a pharmaceutical composition for the prevention, amelioration or treatment of various diseases by selectively eliminating specific proteins.

Photoactivable nonsymmetrical bifunctional linkers for protein immobilization on attenuated total reflectance FTIR optical devices

The photosensitive 4-azido-2,3,5,6-tetrafluoro-1-benzoyl core has been connected to maleimide-, chloroacetyloxy-, or succinimidyl carbonate motifs through various spacers to furnish a series of bifunctional linkers. One linker (7a) has been used for the construction of a biosensor for β-lactam antibiotic detection by attenuated total reflectance FTIR (ATR-FTIR) spectroscopy. Linkers featuring a photosensitive aryl azide motif at one end and a function reactive toward nucleophiles at the other end are described. One linker is used for the construction of a biosensor for β-lactam antibiotic detection by attenuated total reflectance FTIR spectroscopy. Copyright

Modular synthesis of bifunctional linkers for materials science

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