430459-44-2

Upstream product

• 165047-24-5 2,4,5-trifluorobenzaldehyde 
• 327-52-6 1-bromo-2,4,5-trifluorobenzene 
• 156217-21-9 bis(2,4,5-trifluorophenyl)methanone 
• 1350807-56-5 bis(2,4,5-trifluorophenyl)methanol 
• 98349-22-5 2,4,5-trifluorobenzonitrile 
• 430459-35-1 5-fluoro-2,4-dimethoxy-benzoic acid 
• 17715-70-7 1,3-dimethoxy-4-fluorobenzene 
• 430459-61-3 5-fluoro-2,4-dimethoxy-benzonitrile 
• 195136-62-0 1-Fluoro-2,4-dimethoxy-5-nitro-benzene 
• 195136-65-3 1-Amino-2,4-dimethoxy-5-fluorobenzene 
• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 879288-15-0 1-fluoro-5-iodo-2,4-dimethoxybenzene 
• 879288-16-1 bis(5-fluoro-2,4-dimethoxyphenyl)methanone 

Downstream Products

• 879288-18-3 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoic acid methyl ester 
• 879288-14-9 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoic acid 
• 952053-74-6 1-{[4-(2,7-difluoro-6-hydroxy-3-oxo-xanthen-9-yl)-3-methylbenzoyl]oxy}pyrrolidine-2,5-dione 
• 879288-21-8 N-[4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoyl]-β-alanyl-N-(3-{(3β)-cholest-5-en-3-yl[(2-nitrophenyl)sulfonyl]amino}propyl)-β-alaninamide 
• 430459-94-2 ({2-benzyloxycarbonylmethoxy-4-[2,7-difluoro-9-hydroxy-3,6-bis(2-methoxyethoxymethoxy)-9H-xanthen-9-yl]-phenyl}-tert-butoxycarbonylmethyl-amino)-acetic acid tert-butyl ester 
• 430459-77-1 ({2-benzyloxy-4-[2,7-difluoro-9-hydroxy-3,6-bis(2-methoxyethoxymethoxy)-9H-xanthen-9-yl]-phenyl}-tert-butoxycarbonylmethyl-amino)-acetic acid tert-butyl ester 
• 430459-82-8 {2-[bis(tert-butoxycarbonylmethyl)amino]-5-[2,7-difluoro-9-hydroxy-3,6-bis(2-methoxyethoxymethoxy)-9H-xanthen-9-yl]-phenoxy}-acetic acid 
• 430459-89-5 (tert-butoxycarbonylmethyl-{4-[2,7-difluoro-9-hydroxy-3,6-bis(2-methoxyethoxymethoxy)-9H-xanthen-9-yl]-2-hydroxy-phenyl}-amino)-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

Efficient and scalable synthesis of 4-carboxy-pennsylvania green methyl ester: A hydrophobic building block for fluorescent molecular probes

Fluorinated fluorophores are valuable tools for studies of biological systems. However, amine-reactive single-isomer derivatives of these compounds are often very expensive. To provide an inexpensive alternative, we developed a practical synthesis of 4-ca

Fluorescent assays for protein kinases

This invention provides fluorescently-labeled peptide substrates for protein kinases; methods using the substrates for identifying compounds that inhibit protein kinases, for determining if particular protein kinases are active in cells, for diagnosing di

The Pennsylvania Green fluorophore: A hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes

Fluorescent small molecules are powerful tools for exploring cellular biology. As a more hydrophobic, photostable, and less pH-sensitive alternative to fluorescein, we synthesized Pennsylvania Green, a bright, monoanionic fluorophore related to Oregon Gre

Design and synthesis of a fluorescent reporter of protein kinase activity

There is widespread interest in developing fluorescent reporters of protein kinase activity, species that can furnish a visual readout of both when and where intracellular kinases are activated in response to a stimulus. We have constructed and identified