431058-46-7

Basic information

• Product Name: ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
• Synonyms: ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate;Levofloxacin Impurity 1;(S)-ethyl 10-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate;Levofloxacin Impurity I
• CAS NO: 431058-46-7
• Molecular Formula: C15H14FNO4
• Molecular Weight: 291.2743632
• Mol File: 431058-46-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 422.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: -3.37±0.60(Predicted)
• CAS DataBase Reference: ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate(431058-46-7)
• EPA Substance Registry System: ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate(431058-46-7)

Safety Data

• Hazardous Substances Data: 431058-46-7(Hazardous Substances Data)

Upstream product

• 157766-27-3 ethyl 3-(2,3,4-trifluorophenyl)-3-oxopropanoate 
• 157373-08-5 2,3,4-trifluoro-benzoyl chloride 
• 601490-35-1 (Z)-3-((S)-2-Hydroxy-1-methyl-ethylamino)-2-(2,3,4-trifluoro-benzoyl)-acrylic acid ethyl ester 

Downstream Products

• 117620-85-6 levofloxacin 
• 117620-84-5 9-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid 

Relevant articles and documents

Synthesis and biological testing of non-fluorinated analogues of Levofloxacin

Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.