601490-35-1 Usage
Uses
2,3,4-Trifluoro-α-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-β-oxo-benzenepropanoic Acid Ethyl Ester is an trifluorinated analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.
Check Digit Verification of cas no
The CAS Registry Mumber 601490-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,1,4,9 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 601490-35:
(8*6)+(7*0)+(6*1)+(5*4)+(4*9)+(3*0)+(2*3)+(1*5)=121
121 % 10 = 1
So 601490-35-1 is a valid CAS Registry Number.
601490-35-1Relevant articles and documents
Synthesis and biological testing of non-fluorinated analogues of Levofloxacin
Gray, Jeffrey L.,Almstead, Ji-In K.,Gallagher, Corey P.,Hu, X. Eric,Kim, Nick K.,Taylor, Cynthia J.,Twinem, Tracy L.,Wallace, Cynthia D.,Ledoussal, Benoit
, p. 2373 - 2375 (2007/10/03)
Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.