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2,3,4-Trifluoro-α-[[[(1S)-2-hydroxy-1-Methylethyl]aMino]Methylene]-β-oxo-benzenepropanoic Acid Ethyl Ester is a trifluorinated analogue of Levofloxacin (L360000), an advanced chemical compound with potent antibiotic properties. It is characterized by its unique molecular structure, which includes a trifluoromethyl group and an ethyl ester functional group, contributing to its enhanced activity against specific bacterial strains.

601490-35-1

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601490-35-1 Usage

Uses

Used in Pharmaceutical Industry:
2,3,4-Trifluoro-α-[[[(1S)-2-hydroxy-1-Methylethyl]aMino]Methylene]-β-oxo-benzenepropanoic Acid Ethyl Ester is used as an antibiotic agent for the treatment of bacterial infections, particularly those caused by gram-negative organisms. Its trifluorinated structure enhances its activity and effectiveness against these bacteria, making it a valuable addition to the arsenal of antibiotics available for combating drug-resistant infections.
Additionally, due to its structural similarity to Levofloxacin, it may also be used in research and development for the creation of new antibiotics or the improvement of existing ones, further contributing to the fight against antibiotic resistance.

Check Digit Verification of cas no

The CAS Registry Mumber 601490-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,1,4,9 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 601490-35:
(8*6)+(7*0)+(6*1)+(5*4)+(4*9)+(3*0)+(2*3)+(1*5)=121
121 % 10 = 1
So 601490-35-1 is a valid CAS Registry Number.

601490-35-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-ethyl 3-((1-hydroxypropan-2-yl)amino)-2-(2,3,4-trifluorobenzoyl)acrylate

1.2 Other means of identification

Product number -
Other names 2,3,4-Trifluoro-Alpha-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-Beta-oxo-benzenepropanoic Acid Ethyl Ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:601490-35-1 SDS

601490-35-1Relevant academic research and scientific papers

Synthesis and biological testing of non-fluorinated analogues of Levofloxacin

Gray, Jeffrey L.,Almstead, Ji-In K.,Gallagher, Corey P.,Hu, X. Eric,Kim, Nick K.,Taylor, Cynthia J.,Twinem, Tracy L.,Wallace, Cynthia D.,Ledoussal, Benoit

, p. 2373 - 2375 (2007/10/03)

Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.

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