43154-30-9

Basic information

• Product Name: N-[2-(4-methylphenylsulfonamido)phenyl]acetamide
• Synonyms: N-[2-(4-methylphenylsulfonamido)phenyl]acetamide
• CAS NO: 43154-30-9
• Molecular Weight: 304.37
• Mol File: 43154-30-9.mol

Chemical Properties

• CAS DataBase Reference: N-[2-(4-methylphenylsulfonamido)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(4-methylphenylsulfonamido)phenyl]acetamide(43154-30-9)
• EPA Substance Registry System: N-[2-(4-methylphenylsulfonamido)phenyl]acetamide(43154-30-9)

Safety Data

• Hazardous Substances Data: 43154-30-9(Hazardous Substances Data)

Upstream product

• 941-55-9 4-toluenesulfonyl azide 
• 103-84-4 Acetanilid 
• 1859-70-7 N-(2-acetylphenyl)-4-methylbenzenesulfonamide 
• 98-86-2 acetophenone 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Iridium-catalyzed direct arene C-H bond amidation with sulfonyl- and aryl azides

Iridium-catalyzed direct ortho C-H amidation of arenes has been shown to work well with sulfonyl- and aryl azides as the nitrogen source. The reaction proceeds efficiently with a broad range of substrates bearing conventional directing groups with excellent functional group compatibility under mild conditions. In addition, substrates forming not only 5- but also 6-membered iridacycle intermediates undergo the C-H amidation with high selectivity.

Ruthenium-catalyzed direct C-H amidation of arenes including weakly coordinating aromatic ketones

C-H activation: The ruthenium-catalyzed direct sp2 C-H amidation of arenes by using sulfonyl azides as the amino source is presented (see scheme). A wide range of substrates were readily amidated including arenes bearing weakly coordinating groups. Synthetic utility of the thus obtained products was demonstrated in the preparation of biologically active heterocycles. Copyright