43188-86-9 Usage
Uses
Used in Pharmaceutical Industry:
11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME is used as an immunogen for the production of antiserum in New Zealand white rabbits. This application is crucial in the development of diagnostic tests and therapies related to steroid hormones.
Used in Fecal Steroid Hormone Processing and Analysis:
In the field of endocrinology and environmental science, 11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME is utilized in the processing and analysis of fecal steroid hormones. This application aids in the non-invasive monitoring of hormonal levels and has significant implications for wildlife conservation, stress assessment, and reproductive health studies.
Used in Research and Development:
As a model steroid, 11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME plays a vital role in research and development, particularly in the study of steroid hormone synthesis, metabolism, and their effects on various physiological processes. This knowledge contributes to the advancement of pharmaceuticals, nutraceuticals, and other related products.
Biochem/physiol Actions
Hydrocortisone 3-(O-carboxymethyl)oxime is used as the analog of cortisol. It is used to modify the surface of an Au chip.
Check Digit Verification of cas no
The CAS Registry Mumber 43188-86-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,1,8 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 43188-86:
(7*4)+(6*3)+(5*1)+(4*8)+(3*8)+(2*8)+(1*6)=129
129 % 10 = 9
So 43188-86-9 is a valid CAS Registry Number.
InChI:InChI=1/C23H33NO7/c1-21-7-5-14(24-31-12-19(28)29)9-13(21)3-4-15-16-6-8-23(30,18(27)11-25)22(16,2)10-17(26)20(15)21/h9,15-17,20,25-26,30H,3-8,10-12H2,1-2H3,(H,28,29)/b24-14+/t15-,16-,17-,20?,21-,22-,23-/m0/s1
43188-86-9Relevant academic research and scientific papers
Hydrocortisone hapten, hydrocortisone artificial antigen and preparation method and application of hydrocortisone artificial antigen
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Paragraph 0025-0026, (2019/03/28)
The invention discloses hydrocortisone hapten, hydrocortisone artificial antigen and a preparation method and application of the hydrocortisone artificial antigen. The hydrocortisone artificial antigen provided herein is an antigen prepared by coupling the hydrocortisone hapten shown as formula I to a carrier protein. The hydrocortisone artificial antigen provided herein is simple to synthesize, high in purity and yield and is important to the preparation of hydrocortisone antibodies and the detection of hydrocortisone drug residue.
Aminoalkylmaleimides and hapten and antigen derivatives derived therefrom as well as conjugates with peptides or proteins
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, (2008/06/13)
The invention concerns new aminoalkylmaleimides of the general formula I STR1 in which R1 and R2 are the same or different and represent hydrogen or a C1 -C4 alkyl group and A represents a straight-chain or branched, saturated or unsaturated alkylene group with 2 to 6 carbon atoms which is interrupted, if desired, by an oxygen or sulphur atom or a carbonyl group, as well as their corresponding acid addition salts. The present invention also concerns amidoalkylmaleimide derivatives formed from compounds of the general formula I and immunological binding partners. In addition, the invention concerns immunological conjugates which can be produced by reaction of the amidoalkylmaleimide derivatives with peptides or proteins. The subject matter of the present invention are also the corresponding processes of production of the compounds according to the present invention as well as the use of these conjugates in diagnostic methods of determination, in particular in immunoassays.
