431897-30-2

Basic information

• Product Name: 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole
• Synonyms: 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole;6-chloro-7-Methoxy-8-nitro-9H-β-carboline
• CAS NO: 431897-30-2
• Molecular Formula: C12H8ClN3O3
• Molecular Weight: 277.66322
• Mol File: 431897-30-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole(431897-30-2)
• EPA Substance Registry System: 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole(431897-30-2)

Safety Data

• Hazardous Substances Data: 431897-30-2(Hazardous Substances Data)

Usage

General Description

6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole is a chemical compound with the molecular formula C14H9ClN2O3. It is a heterocyclic compound with a pyridoindole structure, containing a chlorine atom, a methoxy group, and a nitro group. 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole is commonly used as a starting material in the synthesis of various organic compounds and pharmaceuticals. It has potential applications in the field of medicinal chemistry and drug development due to its unique structural features and biological activities. Additionally, it is important to handle 6-chloro-7-Methoxy-8-nitro-9H-pyrido[3,4-b]indole with caution due to its potential toxicity and harmful effects on the environment.

Upstream product

• 783349-34-8 6-chloro-7-fluoro-8-nitro-9H-β-carboline 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 

Downstream Products

• 431886-96-3 6-chloro-7-methoxy-9H-β-carbolin-8-ylamine 

Relevant articles and documents

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.

BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE

This invention provides beta-carboline compounds of formula (I) wherein Ring A is a substituted pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring and R1, R2 and R3 are as described in the specification. The compounds are IKK-2 inhibitors that are useful for treating IKK-2 mediated diseases such as inflammatory diseases and cancer.

Substituted beta-carbolines

Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in whose course an increased activity of IκB kinase is involved.