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methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 432016-21-2 Structure
  • Basic information

    1. Product Name: methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate
    2. Synonyms: methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate
    3. CAS NO:432016-21-2
    4. Molecular Formula:
    5. Molecular Weight: 319.381
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 432016-21-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate(432016-21-2)
    11. EPA Substance Registry System: methyl 4-methyl-3-((4-methylphenyl)sulfonamido)benzoate(432016-21-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 432016-21-2(Hazardous Substances Data)

432016-21-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 432016-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,2,0,1 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 432016-21:
(8*4)+(7*3)+(6*2)+(5*0)+(4*1)+(3*6)+(2*2)+(1*1)=92
92 % 10 = 2
So 432016-21-2 is a valid CAS Registry Number.

432016-21-2Relevant articles and documents

Metal-Free Catalyzed Cyclization of N-Methoxybenzamides to Construct Quaternary Carbon-Containing Isoindolinones

Zhang, Lin-Bao,Wang, Zi-Chen,Sun, Sheng-Zheng,Ni, Shao-Fei,Wen, Li-Rong,Li, Ming

, p. 903 - 908 (2021)

Through the intramolecular cyclization of N-methoxybenzamides, a simple and efficient method for constructing valuable isoindolinones under metal-free conditions was developed. The reaction was featured by employing low-cost catalyst, simple operation, 100% atomic economy and excellent regioselectivity. Moreover, a detailed computational study on the reaction system has been performed to clarify the mechanism. This protocol tolerated a variety of functional groups and provided a metal-free protocol for the synthesis of chromane- or tetrahydroquinoline-fused isoindolinones in good yields.

Pyrazole compound, preparation method and application thereof, and pharmaceutical composition

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Paragraph 0099-0105, (2020/07/08)

The invention relates to a substituted pyrazole compound, a preparation method and application thereof, and a pharmaceutical composition, wherein the pyrazole compound is represented by a formula (I),is an STAT3 signal channel inhibitor, and can be used for preventing and/or treating diseases related to STAT3 activity, such as tumors, autoimmune diseases, kidney diseases, cardiovascular diseases,inflammatory diseases, metabolic/endocrine dysfunction or neurological diseases.

Toluidinesulfonamide hypoxia-induced factor 1 inhibitors: Alleviating drug-drug interactions through use of pubchem data and comparative molecular field analysis guided synthesis

Wendt, Bernd,Mülbaier, Marcel,Wawro, Sabine,Schultes, Christoph,Alonso, Jorge,Janssen, Bernd,Lewis, Joe

experimental part, p. 3982 - 3986 (2011/08/05)

Inhibitors of hypoxia-inducible factor 1 (HIF-1) represent promising anticancer therapeutics. We have identified a series of potent toluidinesulfonamide HIF-1 inhibitors. However, the series was threatened by a potential liability to inhibit CYP2C9 which could cause dangerous drug-drug interactions when being coadministered with other drugs. We used structure-activity data from the PubChem database to develop a topomer CoMFAmodel that guided the design of novel sulfonamides with high selectivity for HIF-1 over CYP2C9 inhibition.

INHIBITORS OF CELL PROLIFERATION AND USES THEREOF

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Page/Page column 30, (2009/10/21)

The present invention provides novel compounds that inhibit cell proliferation and uses of these compounds for treating, ameliorating or preventing diseases, conditions or disorders benefiting from the inhibition hyperproliferation.

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