4323-80-2

Basic information

• Product Name: demethoxysudachitin
• Synonyms: demethoxysudachitin;3'-Demethoxysudachitin;4',5,7-Trihydroxy-6,8-dimethoxyflavone
• CAS NO: 4323-80-2
• Molecular Formula: C₁₇H₁₄O₇
• Molecular Weight: 330.28886
• Mol File: 4323-80-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 650.7°C at 760 mmHg
• Flash Point: 244.2°C
• Appearance: /
• Density: 1.483g/cm³
• Vapor Pressure: 1.57E-17mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: demethoxysudachitin(CAS DataBase Reference)
• NIST Chemistry Reference: demethoxysudachitin(4323-80-2)
• EPA Substance Registry System: demethoxysudachitin(4323-80-2)

Safety Data

• Hazardous Substances Data: 4323-80-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H14O7/c1-22-16-13(20)12-10(19)7-11(8-3-5-9(18)6-4-8)24-15(12)17(23-2)14(16)21/h3-7,18,20-21H,1-2H3

Upstream product

• 520-36-5 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 
• 480-41-1 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on 
• 1006032-73-0 6,8-dibromo-5,7,4'-trihydroxyflavone 
• 124-41-4 sodium methylate 

Downstream Products

• 481-53-8 tangeritin 

Relevant articles and documents

Semisynthesis of polymethoxyflavonoids from naringin and hesperidin

Polymethoxyflavonoids (PMFs) possess important biological activities, notably as anticancer agents. Semisynthesis of a series of PMFs were performed by glycoside hydrolysis, dehydrogenation, bromination, aromatic nucleophilic substitution, O-methylation, dimethyldioxirane oxidation and regioselective demethylation, starting from abundant and inexpensive natural sources naringin and hesperidin. A new synthetic method for selective methylation using CuBr catalysed and microwave-assisted reaction was developed, and the dimethyl dioxirane oxidation of flavones to flavonols was much improved. The new semisynthetic route has the advantages of easy availability of starting materials, simple operation and good yields.

Radical-scavenging polyphenols: New strategies for their synthesis

New strategies for the synthesis of polyphenols, compounds with antioxidant properties contained in every kind of plants, are discussed. Syntheses of different classes of polyphenols, namely ubiquinones, present in many natural systems in which electron-transfer mechanisms are involved, hydroxytyrosol, one of the main components of the phenol fraction in olives, and flavonoids, widespread in the plant kingdom, were approached by simple and environmentally sustainable methods.