4330-14-7

Usage

Uses

Used in Pharmaceutical Development:
2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoylis used as a reagent in the preparation of various heterocyclic compounds, which are essential building blocks in the development of pharmaceuticals. Its potential applications in the field of medicine include the development of drugs for the treatment of various diseases and disorders.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoylplays a crucial role in the synthesis of complex organic compounds. Its versatility in chemical reactions allows for the creation of a wide range of molecules with diverse applications.
Used in Dye Production:
2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoylis also used in the production of certain dyes. Its unique chemical properties contribute to the development of dyes with specific characteristics, such as color intensity and stability.

Upstream product

• 98-88-4 benzoyl chloride 
• 66-22-8 uracil 

Downstream Products

• 860267-02-3 3-benzoyl-1-(5-benzoyloxypentyl)uracil 
• 860266-98-4 3-benzoyl-1-[(Z)-4-trityloxy-2-butenyl]uracil 
• 860266-99-5 3-benzoyl-1-[(E)-4-trityloxy-2-butenyl]uracil 
• 860267-00-1 3-benzoyl-1-(5-trityloxypentyl)uracil 
• 860267-01-2 3-benzoyl-1-(5-tritylaminopentyl)uracil 
• 365515-76-0 1-cyclopentyl-3-benzoyluracil 
• 365515-75-9 N¹-allyl-N³-benzoyluracil 
• 316352-69-9 3-benzoyl-1-ethyluracil 
• 2775-87-3 3-N-benzoyluracil 

Relevant academic research and scientific papers

A short synthesis of 1-vinyluracil and 1-vinylthymine

1-Vinyluracil and 1-vinylthymine, monomers for nucleic acid bases attached functional polymers, were synthesized for the first time from uracil and thymine in 3 steps in 54% and 50% overall yields using the Mitsunobu reactions of 2a and 2b with 2-chloroet

Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase

We report the discovery of novel uracil-based acyclic compounds as inhibitors of deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase), an enzyme involved in nucleotide metabolism that has been identified as a promising target for the development of

Synthesis of difluorocyclopropyl carbocyclic homo-nucleosides

Racemic difluorinated carbocyclic homo-nucleoside analogues are easily accessible from (Z)-4-(benzyloxy)-2-butenyl acetate by difluorocyclopropanation using sodium chlorodifluoro acetate in diglyme at 190°C followed by Mitsunobu reactions.

THE BENZOYLATION OF URACIL AND THYMINE

Uracil and thymine react with benzoyl chloride in acetonitrile-pyridine solution at room temperature to give first their 1-N-benzoyl (2b and 3b) and then their 1-N,3-N-dibenzoyl derivatives (4a and 4b, respectively); the latter compounds are converted into the corresponding 3-N-benzoyl derivatives (5a and 6a) under mild conditions of basic hydrolysis.