433683-47-7

Usage

Uses

Used in Pharmaceutical Research:
5-BROMO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIMIDINE is used as a building block for the synthesis of various biologically active compounds, playing a crucial role in the development of new drugs.
Used in Agrochemicals:
In the agrochemical industry, 5-BROMO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIMIDINE is used as a key intermediate for the creation of compounds with potential applications in agriculture, such as pesticides or herbicides.
Used in Material Science:
5-BROMO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIMIDINE is utilized as a component in the development of new materials, thanks to its unique properties that can enhance material characteristics in various applications.

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 62802-38-4 5-fluoro-2-(trifluoromethyl)pyrimidine 
• 6226-25-1 2,2,2-trifluoroethyl trifluoromethanesulphonate 
• 38353-06-9 5-bromopyrimidin-2-ol 
• 32779-37-6 2,5-dibromopyrimidine 
• 855719-15-2 trifluoroethanol 
• 38275-48-8 5-bromo-2-(methylsulfonyl)pyrimidine 

Downstream Products

• 433683-46-6 5-{4-[5-(2,6-difluorophenyl)-3,4-dihydro-2H-pyrrol-2-yl]phenyl}-2-(2,2,2-trifluorethoxy)pyrimidine 
• 1351234-12-2 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2,2,2-trifluoroethoxy)pyrimidine 
• 1401163-85-6 [2-(2,2,2-trifluoroethoxy)pyrimidin-5-yl]boronic acid 

Relevant academic research and scientific papers

SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES

Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.

SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES

Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.

HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE

The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase ("D5D"). The compounds have a general Formula (I): wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

PYRIDAZINONE COMPOUNDS AND USES THEREOF

Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.

PYRIDAZINONE COMPOUNDS AND USES THEREOF

Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.

AROMATIC COMPOUND

Provided is a novel aromatic ring compound which may have a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof may have a GPR40 agoni

DIHYDROOXAZOL-2-AMINE DERIVATIVES

The invention relates to compounds of formula wherein R1, R2, R3, R4, X, Ar, and are defined herein or to a pharmaceutically suitable acid addition salt thereof. Compounds of formula I have a good affinity to th

Thieno-pyrimidine compounds having fungicidal activity

The present invention relates to thieno[2,3-d]-pyrimidine compounds having fungicidal activity.