433693-72-2Relevant academic research and scientific papers
Efficient synthesis of a novel series of indeno-fused pyrido[2,3-d]pyrimidines using a deep eutectic solvent system comprised of choline chloride/urea
Roknabadi, Mohammad Hakimi,Mosslemin, Mohammad Hossein,Mohebat, Razieh
, p. 430 - 433 (2017)
A series of 13 aryl indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6-(3H,5H,11H)-triones, eight of which are new, were synthesised regioselectively in high yields by a three-component reaction of 1,3-indanedione, an araldehyde and 6-aminopyrimidin-2,4(1H,3H
Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents
Evdokimov, Nikolai M.,Van Slambrouck, Severine,Heffeter, Petra,Tu, Lee,Le Calvé, Benjamin,Lamoral-Theys, Delphine,Hooten, Carla J.,Uglinskii, Pavel Y.,Rogelj, Snezna,Kiss, Robert,Steelant, Wim F.A.,Berger, Walter,Yang, Jeremy J.,Bologa, Cristian G.,Kornienko, Alexander,Magedov, Igor V.
experimental part, p. 2012 - 2021 (2011/06/10)
After the initial discovery of antiproliferative and apoptosis-inducing properties of a camptothecin-inspired pentacycle based on a 1H-indeno[2′, 1′:5,6]dihydropyrido[2,3-d]pyrimidine scaffold, a library of its analogues as well as their oxidized planar c
