433939-88-9

Basic information

• Product Name: 4-CYANO-3,5-DIFLUORO BENZALDEHYDE
• Synonyms: 2,6-DIFLUORO-4-FORMYLBENZONITRILE
• CAS NO: 433939-88-9
• Molecular Formula: C₈H₃F₂NO
• Molecular Weight: 167.11
• Product Categories: Liquid Crystal intermediates;Nitrile
• Mol File: 433939-88-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 48-50℃
• Boiling Point: 263℃
• Flash Point: 113℃
• Appearance: Light yellow cryst.
• Density: 1.35
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.505
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-CYANO-3,5-DIFLUORO BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-3,5-DIFLUORO BENZALDEHYDE(433939-88-9)
• EPA Substance Registry System: 4-CYANO-3,5-DIFLUORO BENZALDEHYDE(433939-88-9)

Safety Data

• Hazardous Substances Data: 433939-88-9(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow Cryst

InChI:InChI=1/C8H3F2NO/c9-7-1-5(4-12)2-8(10)6(7)3-11/h1-2,4H

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 123843-67-4 4-bromo-2,6-difluorobenzonitrile 
• 32085-88-4 3,5-difluorobenzaldehyde 
• 717883-47-1 4-[1,3]dioxolan-2-yl-2,6-difluoro-benzonitrile 
• 479621-01-7 2,6-difluoro-4-[(methylsulfinyl)(methylthio)methyl]benzonitrile 
• 197785-23-2 2-(3,5-difluorophenyl)-1,3-dioxolane 

Downstream Products

• 433939-89-0 2,6-difluoro-4-(hydroxymethyl)benzonitrile 

Relevant articles and documents

THIAZOLE DERIVATIVES FOR THE TREATMENT OF ANIMAL TRYPANOSOMIASIS

The present invention relates to a novel class of compounds of general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, X and Y are as defined herein, to their use in human and veterinary medicine, and in the treatment of animal trypanosomiasis in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: Effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions

The H-atoms of the phenylamidinium needle of tricyclic thrombin inhibitors, which interacts with Asp189 at the bottom of the selectivity pocket S1 of the enzyme, were systematically exchanged with F-atoms in an attempt to improve the pharmacokinetic prope