433970-55-9Relevant academic research and scientific papers
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening
Xiong, Huan,Han, Jie,Wang, Jun,Lu, Wenchao,Wang, Chen,Chen, Yu,Fulin Lian,Zhang, Naixia,Liu, Yu-Chih,Zhang, Chenhua,Ding, Hong,Jiang, Hualiang,Lu, Wencong,Luo, Cheng,Zhou, Bing
, p. 740 - 751 (2018)
The general control nonrepressed protein 5 (GCN5) plays a crucial role in many biological processes. Dysregulation of GCN5 has been closely related to various human diseases, especially cancers. Hence, the exploitation of small molecules targeting GCN5 is
